STUDIES ON PATHOGENIC B. COLI FROM BOVINE SOURCES : II. MUTATIONS AND THEIR IMMUNOLOGICAL SIGNIFICANCE.

On agar plates certain strains of B. coli from the ileum of calves suffering from diarrhea or scours promptly mutate and give rise to forms which have lost capsular substance, whose virulence has been greatly reduced, and which have gained very greatly in agglutinability and in being taken up by leu...

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Detalles Bibliográficos
Autores principales: Smith, Theobald, Bryant, Gladys
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1927
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131249/
https://www.ncbi.nlm.nih.gov/pubmed/19869320
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author Smith, Theobald
Bryant, Gladys
author_facet Smith, Theobald
Bryant, Gladys
author_sort Smith, Theobald
collection PubMed
description On agar plates certain strains of B. coli from the ileum of calves suffering from diarrhea or scours promptly mutate and give rise to forms which have lost capsular substance, whose virulence has been greatly reduced, and which have gained very greatly in agglutinability and in being taken up by leucocytes. The original characters are not regained in cultures kept in the cold after development, nor in rapid transfers in bouillon, nor in passages through the peritoneal cavity of guinea pigs. Filtrates of 48 hour bouillon cultures contain as much toxin in the (b) as in the (a) form indicating no loss in this function.
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spelling pubmed-21312492008-04-18 STUDIES ON PATHOGENIC B. COLI FROM BOVINE SOURCES : II. MUTATIONS AND THEIR IMMUNOLOGICAL SIGNIFICANCE. Smith, Theobald Bryant, Gladys J Exp Med Article On agar plates certain strains of B. coli from the ileum of calves suffering from diarrhea or scours promptly mutate and give rise to forms which have lost capsular substance, whose virulence has been greatly reduced, and which have gained very greatly in agglutinability and in being taken up by leucocytes. The original characters are not regained in cultures kept in the cold after development, nor in rapid transfers in bouillon, nor in passages through the peritoneal cavity of guinea pigs. Filtrates of 48 hour bouillon cultures contain as much toxin in the (b) as in the (a) form indicating no loss in this function. The Rockefeller University Press 1927-06-30 /pmc/articles/PMC2131249/ /pubmed/19869320 Text en Copyright © Copyright, 1927, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Smith, Theobald
Bryant, Gladys
STUDIES ON PATHOGENIC B. COLI FROM BOVINE SOURCES : II. MUTATIONS AND THEIR IMMUNOLOGICAL SIGNIFICANCE.
title STUDIES ON PATHOGENIC B. COLI FROM BOVINE SOURCES : II. MUTATIONS AND THEIR IMMUNOLOGICAL SIGNIFICANCE.
title_full STUDIES ON PATHOGENIC B. COLI FROM BOVINE SOURCES : II. MUTATIONS AND THEIR IMMUNOLOGICAL SIGNIFICANCE.
title_fullStr STUDIES ON PATHOGENIC B. COLI FROM BOVINE SOURCES : II. MUTATIONS AND THEIR IMMUNOLOGICAL SIGNIFICANCE.
title_full_unstemmed STUDIES ON PATHOGENIC B. COLI FROM BOVINE SOURCES : II. MUTATIONS AND THEIR IMMUNOLOGICAL SIGNIFICANCE.
title_short STUDIES ON PATHOGENIC B. COLI FROM BOVINE SOURCES : II. MUTATIONS AND THEIR IMMUNOLOGICAL SIGNIFICANCE.
title_sort studies on pathogenic b. coli from bovine sources : ii. mutations and their immunological significance.
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131249/
https://www.ncbi.nlm.nih.gov/pubmed/19869320
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