THE PRODUCTION OF SKIN NECROSIS BY CERTAIN AUTOLYSATES OF PNEUMOCOCCUS (TYPES I AND II)

1. Certain pneumococcus autolysates produce necrosis when injected into the skin of guinea pigs. 2. The necrosis-producing principle can be filtered through a Berkefeld N filter, is extremely thermolabile, and is very sensitive to oxidation. 3. The necrotizing poison can be separated from the pneumo...

Descripción completa

Detalles Bibliográficos
Autor principal: Parker, Julia T.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1928
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131390/
https://www.ncbi.nlm.nih.gov/pubmed/19869429
_version_ 1782142228278280192
author Parker, Julia T.
author_facet Parker, Julia T.
author_sort Parker, Julia T.
collection PubMed
description 1. Certain pneumococcus autolysates produce necrosis when injected into the skin of guinea pigs. 2. The necrosis-producing principle can be filtered through a Berkefeld N filter, is extremely thermolabile, and is very sensitive to oxidation. 3. The necrotizing poison can be separated from the pneumococcus hemotoxin by adsorption with red cells. This removes the hemotoxin and leaves the necrosis-producing principle unaffected. 4. The necrotizing substances obtained from Pneumococcus Types I and II are neutralized by the antiserum prepared with Pneumococcus I.
format Text
id pubmed-2131390
institution National Center for Biotechnology Information
language English
publishDate 1928
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21313902008-04-18 THE PRODUCTION OF SKIN NECROSIS BY CERTAIN AUTOLYSATES OF PNEUMOCOCCUS (TYPES I AND II) Parker, Julia T. J Exp Med Article 1. Certain pneumococcus autolysates produce necrosis when injected into the skin of guinea pigs. 2. The necrosis-producing principle can be filtered through a Berkefeld N filter, is extremely thermolabile, and is very sensitive to oxidation. 3. The necrotizing poison can be separated from the pneumococcus hemotoxin by adsorption with red cells. This removes the hemotoxin and leaves the necrosis-producing principle unaffected. 4. The necrotizing substances obtained from Pneumococcus Types I and II are neutralized by the antiserum prepared with Pneumococcus I. The Rockefeller University Press 1928-03-31 /pmc/articles/PMC2131390/ /pubmed/19869429 Text en Copyright © Copyright, 1928, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Parker, Julia T.
THE PRODUCTION OF SKIN NECROSIS BY CERTAIN AUTOLYSATES OF PNEUMOCOCCUS (TYPES I AND II)
title THE PRODUCTION OF SKIN NECROSIS BY CERTAIN AUTOLYSATES OF PNEUMOCOCCUS (TYPES I AND II)
title_full THE PRODUCTION OF SKIN NECROSIS BY CERTAIN AUTOLYSATES OF PNEUMOCOCCUS (TYPES I AND II)
title_fullStr THE PRODUCTION OF SKIN NECROSIS BY CERTAIN AUTOLYSATES OF PNEUMOCOCCUS (TYPES I AND II)
title_full_unstemmed THE PRODUCTION OF SKIN NECROSIS BY CERTAIN AUTOLYSATES OF PNEUMOCOCCUS (TYPES I AND II)
title_short THE PRODUCTION OF SKIN NECROSIS BY CERTAIN AUTOLYSATES OF PNEUMOCOCCUS (TYPES I AND II)
title_sort production of skin necrosis by certain autolysates of pneumococcus (types i and ii)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131390/
https://www.ncbi.nlm.nih.gov/pubmed/19869429
work_keys_str_mv AT parkerjuliat theproductionofskinnecrosisbycertainautolysatesofpneumococcustypesiandii
AT parkerjuliat productionofskinnecrosisbycertainautolysatesofpneumococcustypesiandii

Ejemplares similares