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THE ANTIGENIC COMPLEX OF STREPTOCOCCUS HÆMOLYTICUS : IV. ANAPHYLAXIS WITH TWO NON-TYPE-SPECIFIC FRACTIONS.
The anaphylactic reactions of two non-type-specific fractions of hemolytic streptococcus extracts parallel the precipitin reactions. The nucleoprotein, P, is a true antigen, in that it stimulates antibody production in rabbits, as shown before, and produces anaphylactic shock in guinea pigs actively...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1928
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131440/ https://www.ncbi.nlm.nih.gov/pubmed/19869449 |
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author | Lancefield, Rebecca C. |
author_facet | Lancefield, Rebecca C. |
author_sort | Lancefield, Rebecca C. |
collection | PubMed |
description | The anaphylactic reactions of two non-type-specific fractions of hemolytic streptococcus extracts parallel the precipitin reactions. The nucleoprotein, P, is a true antigen, in that it stimulates antibody production in rabbits, as shown before, and produces anaphylactic shock in guinea pigs actively as well as passively. The probable carbohydrate, C, on the other hand, does not induce antibody formation in rabbits, so far as known at present, but does produce typical anaphylactic shock in guinea pigs passively sensitized with antibacterial serum provided the serum shows a high titer of C precipitins. This is an instance of a hapten, probably carbohydrate in nature, causing anaphylactic shock in passively sensitized guinea pigs. |
format | Text |
id | pubmed-2131440 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1928 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21314402008-04-18 THE ANTIGENIC COMPLEX OF STREPTOCOCCUS HÆMOLYTICUS : IV. ANAPHYLAXIS WITH TWO NON-TYPE-SPECIFIC FRACTIONS. Lancefield, Rebecca C. J Exp Med Article The anaphylactic reactions of two non-type-specific fractions of hemolytic streptococcus extracts parallel the precipitin reactions. The nucleoprotein, P, is a true antigen, in that it stimulates antibody production in rabbits, as shown before, and produces anaphylactic shock in guinea pigs actively as well as passively. The probable carbohydrate, C, on the other hand, does not induce antibody formation in rabbits, so far as known at present, but does produce typical anaphylactic shock in guinea pigs passively sensitized with antibacterial serum provided the serum shows a high titer of C precipitins. This is an instance of a hapten, probably carbohydrate in nature, causing anaphylactic shock in passively sensitized guinea pigs. The Rockefeller University Press 1928-05-31 /pmc/articles/PMC2131440/ /pubmed/19869449 Text en Copyright © Copyright, 1928, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Lancefield, Rebecca C. THE ANTIGENIC COMPLEX OF STREPTOCOCCUS HÆMOLYTICUS : IV. ANAPHYLAXIS WITH TWO NON-TYPE-SPECIFIC FRACTIONS. |
title | THE ANTIGENIC COMPLEX OF STREPTOCOCCUS HÆMOLYTICUS : IV. ANAPHYLAXIS WITH TWO NON-TYPE-SPECIFIC FRACTIONS. |
title_full | THE ANTIGENIC COMPLEX OF STREPTOCOCCUS HÆMOLYTICUS : IV. ANAPHYLAXIS WITH TWO NON-TYPE-SPECIFIC FRACTIONS. |
title_fullStr | THE ANTIGENIC COMPLEX OF STREPTOCOCCUS HÆMOLYTICUS : IV. ANAPHYLAXIS WITH TWO NON-TYPE-SPECIFIC FRACTIONS. |
title_full_unstemmed | THE ANTIGENIC COMPLEX OF STREPTOCOCCUS HÆMOLYTICUS : IV. ANAPHYLAXIS WITH TWO NON-TYPE-SPECIFIC FRACTIONS. |
title_short | THE ANTIGENIC COMPLEX OF STREPTOCOCCUS HÆMOLYTICUS : IV. ANAPHYLAXIS WITH TWO NON-TYPE-SPECIFIC FRACTIONS. |
title_sort | antigenic complex of streptococcus hæmolyticus : iv. anaphylaxis with two non-type-specific fractions. |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131440/ https://www.ncbi.nlm.nih.gov/pubmed/19869449 |
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