Cargando…

THE ANTIGENIC COMPLEX OF STREPTOCOCCUS HÆMOLYTICUS : IV. ANAPHYLAXIS WITH TWO NON-TYPE-SPECIFIC FRACTIONS.

The anaphylactic reactions of two non-type-specific fractions of hemolytic streptococcus extracts parallel the precipitin reactions. The nucleoprotein, P, is a true antigen, in that it stimulates antibody production in rabbits, as shown before, and produces anaphylactic shock in guinea pigs actively...

Descripción completa

Detalles Bibliográficos
Autor principal: Lancefield, Rebecca C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1928
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131440/
https://www.ncbi.nlm.nih.gov/pubmed/19869449
_version_ 1782142235577417728
author Lancefield, Rebecca C.
author_facet Lancefield, Rebecca C.
author_sort Lancefield, Rebecca C.
collection PubMed
description The anaphylactic reactions of two non-type-specific fractions of hemolytic streptococcus extracts parallel the precipitin reactions. The nucleoprotein, P, is a true antigen, in that it stimulates antibody production in rabbits, as shown before, and produces anaphylactic shock in guinea pigs actively as well as passively. The probable carbohydrate, C, on the other hand, does not induce antibody formation in rabbits, so far as known at present, but does produce typical anaphylactic shock in guinea pigs passively sensitized with antibacterial serum provided the serum shows a high titer of C precipitins. This is an instance of a hapten, probably carbohydrate in nature, causing anaphylactic shock in passively sensitized guinea pigs.
format Text
id pubmed-2131440
institution National Center for Biotechnology Information
language English
publishDate 1928
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21314402008-04-18 THE ANTIGENIC COMPLEX OF STREPTOCOCCUS HÆMOLYTICUS : IV. ANAPHYLAXIS WITH TWO NON-TYPE-SPECIFIC FRACTIONS. Lancefield, Rebecca C. J Exp Med Article The anaphylactic reactions of two non-type-specific fractions of hemolytic streptococcus extracts parallel the precipitin reactions. The nucleoprotein, P, is a true antigen, in that it stimulates antibody production in rabbits, as shown before, and produces anaphylactic shock in guinea pigs actively as well as passively. The probable carbohydrate, C, on the other hand, does not induce antibody formation in rabbits, so far as known at present, but does produce typical anaphylactic shock in guinea pigs passively sensitized with antibacterial serum provided the serum shows a high titer of C precipitins. This is an instance of a hapten, probably carbohydrate in nature, causing anaphylactic shock in passively sensitized guinea pigs. The Rockefeller University Press 1928-05-31 /pmc/articles/PMC2131440/ /pubmed/19869449 Text en Copyright © Copyright, 1928, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Lancefield, Rebecca C.
THE ANTIGENIC COMPLEX OF STREPTOCOCCUS HÆMOLYTICUS : IV. ANAPHYLAXIS WITH TWO NON-TYPE-SPECIFIC FRACTIONS.
title THE ANTIGENIC COMPLEX OF STREPTOCOCCUS HÆMOLYTICUS : IV. ANAPHYLAXIS WITH TWO NON-TYPE-SPECIFIC FRACTIONS.
title_full THE ANTIGENIC COMPLEX OF STREPTOCOCCUS HÆMOLYTICUS : IV. ANAPHYLAXIS WITH TWO NON-TYPE-SPECIFIC FRACTIONS.
title_fullStr THE ANTIGENIC COMPLEX OF STREPTOCOCCUS HÆMOLYTICUS : IV. ANAPHYLAXIS WITH TWO NON-TYPE-SPECIFIC FRACTIONS.
title_full_unstemmed THE ANTIGENIC COMPLEX OF STREPTOCOCCUS HÆMOLYTICUS : IV. ANAPHYLAXIS WITH TWO NON-TYPE-SPECIFIC FRACTIONS.
title_short THE ANTIGENIC COMPLEX OF STREPTOCOCCUS HÆMOLYTICUS : IV. ANAPHYLAXIS WITH TWO NON-TYPE-SPECIFIC FRACTIONS.
title_sort antigenic complex of streptococcus hæmolyticus : iv. anaphylaxis with two non-type-specific fractions.
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131440/
https://www.ncbi.nlm.nih.gov/pubmed/19869449
work_keys_str_mv AT lancefieldrebeccac theantigeniccomplexofstreptococcushæmolyticusivanaphylaxiswithtwonontypespecificfractions
AT lancefieldrebeccac antigeniccomplexofstreptococcushæmolyticusivanaphylaxiswithtwonontypespecificfractions