THE EFFECT OF OXIDATION OF FILTRATES OF A CHICKEN SARCOMA (CHICKEN TUMOR I—ROUS)

1. The rapid autoinactivation at 37° of candle filtrates of the Rous Foul Sarcoma I is due in large part to oxidation. 2. Such oxidation may be prevented by a dilution of 1-2000 cysteine hydrochloride brought to pH 7.4 with NaOH. 3. The variability of infectiousness of candle filtrates is due in par...

Descripción completa

Detalles Bibliográficos
Autor principal: Mueller, J. Howard
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1928
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131470/
https://www.ncbi.nlm.nih.gov/pubmed/19869489
_version_ 1782142242598682624
author Mueller, J. Howard
author_facet Mueller, J. Howard
author_sort Mueller, J. Howard
collection PubMed
description 1. The rapid autoinactivation at 37° of candle filtrates of the Rous Foul Sarcoma I is due in large part to oxidation. 2. Such oxidation may be prevented by a dilution of 1-2000 cysteine hydrochloride brought to pH 7.4 with NaOH. 3. The variability of infectiousness of candle filtrates is due in part at least to oxidative changes which take place during their preparation; and more active extracts may be obtained by preventing these by means of cysteine. 4. For elaborate experiments it is possible to preserve filtrates in the ice box with cysteine and vaseline until test inoculations have established their infectivity.
format Text
id pubmed-2131470
institution National Center for Biotechnology Information
language English
publishDate 1928
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21314702008-04-18 THE EFFECT OF OXIDATION OF FILTRATES OF A CHICKEN SARCOMA (CHICKEN TUMOR I—ROUS) Mueller, J. Howard J Exp Med Article 1. The rapid autoinactivation at 37° of candle filtrates of the Rous Foul Sarcoma I is due in large part to oxidation. 2. Such oxidation may be prevented by a dilution of 1-2000 cysteine hydrochloride brought to pH 7.4 with NaOH. 3. The variability of infectiousness of candle filtrates is due in part at least to oxidative changes which take place during their preparation; and more active extracts may be obtained by preventing these by means of cysteine. 4. For elaborate experiments it is possible to preserve filtrates in the ice box with cysteine and vaseline until test inoculations have established their infectivity. The Rockefeller University Press 1928-08-31 /pmc/articles/PMC2131470/ /pubmed/19869489 Text en Copyright © Copyright, 1928, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Mueller, J. Howard
THE EFFECT OF OXIDATION OF FILTRATES OF A CHICKEN SARCOMA (CHICKEN TUMOR I—ROUS)
title THE EFFECT OF OXIDATION OF FILTRATES OF A CHICKEN SARCOMA (CHICKEN TUMOR I—ROUS)
title_full THE EFFECT OF OXIDATION OF FILTRATES OF A CHICKEN SARCOMA (CHICKEN TUMOR I—ROUS)
title_fullStr THE EFFECT OF OXIDATION OF FILTRATES OF A CHICKEN SARCOMA (CHICKEN TUMOR I—ROUS)
title_full_unstemmed THE EFFECT OF OXIDATION OF FILTRATES OF A CHICKEN SARCOMA (CHICKEN TUMOR I—ROUS)
title_short THE EFFECT OF OXIDATION OF FILTRATES OF A CHICKEN SARCOMA (CHICKEN TUMOR I—ROUS)
title_sort effect of oxidation of filtrates of a chicken sarcoma (chicken tumor i—rous)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131470/
https://www.ncbi.nlm.nih.gov/pubmed/19869489
work_keys_str_mv AT muellerjhoward theeffectofoxidationoffiltratesofachickensarcomachickentumorirous
AT muellerjhoward effectofoxidationoffiltratesofachickensarcomachickentumorirous

Ejemplares similares