STUDIES IN ASTHMA : VII. THE PULMONARY CIRCULATION IN THE GUINEA PIG DURING ANAPHYLACTIC SHOCK.

1. Sheep serum in doses below 0.3 cc. intravenously produces no pulmonary vasoconstriction in the guinea pig. Guinea pigs have consequently been sensitized with this substance and anaphylactic shock produced by doses of O.1 and 0.2 cc. 2. Pressure in the pulmonary artery has been measured by the met...

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Detalles Bibliográficos
Autores principales: Went, Stephen, Drinker, Cecil K.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1929
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131518/
https://www.ncbi.nlm.nih.gov/pubmed/19869534
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author Went, Stephen
Drinker, Cecil K.
author_facet Went, Stephen
Drinker, Cecil K.
author_sort Went, Stephen
collection PubMed
description 1. Sheep serum in doses below 0.3 cc. intravenously produces no pulmonary vasoconstriction in the guinea pig. Guinea pigs have consequently been sensitized with this substance and anaphylactic shock produced by doses of O.1 and 0.2 cc. 2. Pressure in the pulmonary artery has been measured by the method of Drinker and Went (2) and recorded photographically in a new and convenient manner. 3. At a very early stage in anaphylactic shock the pulmonary arterial pressure falls markedly and this fall seems to precede the appearance of bronchiolar obstruction. 4. The fall in pulmonary blood pressure in anaphylactic shock is in marked contrast to the rise in pressure resulting from intravenous injection of toxic foreign protein, such as horse serum.
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spelling pubmed-21315182008-04-18 STUDIES IN ASTHMA : VII. THE PULMONARY CIRCULATION IN THE GUINEA PIG DURING ANAPHYLACTIC SHOCK. Went, Stephen Drinker, Cecil K. J Exp Med Article 1. Sheep serum in doses below 0.3 cc. intravenously produces no pulmonary vasoconstriction in the guinea pig. Guinea pigs have consequently been sensitized with this substance and anaphylactic shock produced by doses of O.1 and 0.2 cc. 2. Pressure in the pulmonary artery has been measured by the method of Drinker and Went (2) and recorded photographically in a new and convenient manner. 3. At a very early stage in anaphylactic shock the pulmonary arterial pressure falls markedly and this fall seems to precede the appearance of bronchiolar obstruction. 4. The fall in pulmonary blood pressure in anaphylactic shock is in marked contrast to the rise in pressure resulting from intravenous injection of toxic foreign protein, such as horse serum. The Rockefeller University Press 1929-01-01 /pmc/articles/PMC2131518/ /pubmed/19869534 Text en Copyright © Copyright, 1929, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Went, Stephen
Drinker, Cecil K.
STUDIES IN ASTHMA : VII. THE PULMONARY CIRCULATION IN THE GUINEA PIG DURING ANAPHYLACTIC SHOCK.
title STUDIES IN ASTHMA : VII. THE PULMONARY CIRCULATION IN THE GUINEA PIG DURING ANAPHYLACTIC SHOCK.
title_full STUDIES IN ASTHMA : VII. THE PULMONARY CIRCULATION IN THE GUINEA PIG DURING ANAPHYLACTIC SHOCK.
title_fullStr STUDIES IN ASTHMA : VII. THE PULMONARY CIRCULATION IN THE GUINEA PIG DURING ANAPHYLACTIC SHOCK.
title_full_unstemmed STUDIES IN ASTHMA : VII. THE PULMONARY CIRCULATION IN THE GUINEA PIG DURING ANAPHYLACTIC SHOCK.
title_short STUDIES IN ASTHMA : VII. THE PULMONARY CIRCULATION IN THE GUINEA PIG DURING ANAPHYLACTIC SHOCK.
title_sort studies in asthma : vii. the pulmonary circulation in the guinea pig during anaphylactic shock.
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131518/
https://www.ncbi.nlm.nih.gov/pubmed/19869534
work_keys_str_mv AT wentstephen studiesinasthmaviithepulmonarycirculationintheguineapigduringanaphylacticshock
AT drinkercecilk studiesinasthmaviithepulmonarycirculationintheguineapigduringanaphylacticshock

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