Cargando…
REACTIONS OF RABBITS TO NON-HEMOLYTIC STREPTOCOCCI : I. GENERAL TUBERCULIN-LIKE HYPERSENSITIVENESS, ALLERGY, OR HYPERERGY FOLLOWING THE SECONDARY REACTION.
1. Accompanying and following the evolution of a secondary reaction in the skin of rabbits after inoculation with suitable doses of certain non-hemolytic streptococci there quickly develops a general state of hypersensitiveness or allergy towards these streptococci. 2. This state is made evident by...
Autores principales: | , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1929
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131572/ https://www.ncbi.nlm.nih.gov/pubmed/19869568 |
_version_ | 1782142262031941632 |
---|---|
author | Derick, C. L. Swift, Homer F. |
author_facet | Derick, C. L. Swift, Homer F. |
author_sort | Derick, C. L. |
collection | PubMed |
description | 1. Accompanying and following the evolution of a secondary reaction in the skin of rabbits after inoculation with suitable doses of certain non-hemolytic streptococci there quickly develops a general state of hypersensitiveness or allergy towards these streptococci. 2. This state is made evident by ophthalmic reactions following corneal inoculations, by much increased reactivity of the skin following intracutaneous reinoculations, and by lethal reactions, resembling tuberculin shock, following intravenous inoculations. 3. In a given hypersensitive rabbit there is a rough parallelism in the intensities of these different kinds of reactions. 4. This type of hypersensitiveness or bacterial allergy does not follow primary intravenous inoculation of rabbits with comparable doses of the streptococci employed. 5. As the development of this type of hypersensitiveness or bacterial allergy seems to accompany the production of focal lesions of a certain intensity, it is probable that in these foci are produced the substances or conditions which lead to this type of bacterial allergy. |
format | Text |
id | pubmed-2131572 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1929 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21315722008-04-18 REACTIONS OF RABBITS TO NON-HEMOLYTIC STREPTOCOCCI : I. GENERAL TUBERCULIN-LIKE HYPERSENSITIVENESS, ALLERGY, OR HYPERERGY FOLLOWING THE SECONDARY REACTION. Derick, C. L. Swift, Homer F. J Exp Med Article 1. Accompanying and following the evolution of a secondary reaction in the skin of rabbits after inoculation with suitable doses of certain non-hemolytic streptococci there quickly develops a general state of hypersensitiveness or allergy towards these streptococci. 2. This state is made evident by ophthalmic reactions following corneal inoculations, by much increased reactivity of the skin following intracutaneous reinoculations, and by lethal reactions, resembling tuberculin shock, following intravenous inoculations. 3. In a given hypersensitive rabbit there is a rough parallelism in the intensities of these different kinds of reactions. 4. This type of hypersensitiveness or bacterial allergy does not follow primary intravenous inoculation of rabbits with comparable doses of the streptococci employed. 5. As the development of this type of hypersensitiveness or bacterial allergy seems to accompany the production of focal lesions of a certain intensity, it is probable that in these foci are produced the substances or conditions which lead to this type of bacterial allergy. The Rockefeller University Press 1929-03-31 /pmc/articles/PMC2131572/ /pubmed/19869568 Text en Copyright © Copyright, 1929, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Derick, C. L. Swift, Homer F. REACTIONS OF RABBITS TO NON-HEMOLYTIC STREPTOCOCCI : I. GENERAL TUBERCULIN-LIKE HYPERSENSITIVENESS, ALLERGY, OR HYPERERGY FOLLOWING THE SECONDARY REACTION. |
title | REACTIONS OF RABBITS TO NON-HEMOLYTIC STREPTOCOCCI : I. GENERAL TUBERCULIN-LIKE HYPERSENSITIVENESS, ALLERGY, OR HYPERERGY FOLLOWING THE SECONDARY REACTION. |
title_full | REACTIONS OF RABBITS TO NON-HEMOLYTIC STREPTOCOCCI : I. GENERAL TUBERCULIN-LIKE HYPERSENSITIVENESS, ALLERGY, OR HYPERERGY FOLLOWING THE SECONDARY REACTION. |
title_fullStr | REACTIONS OF RABBITS TO NON-HEMOLYTIC STREPTOCOCCI : I. GENERAL TUBERCULIN-LIKE HYPERSENSITIVENESS, ALLERGY, OR HYPERERGY FOLLOWING THE SECONDARY REACTION. |
title_full_unstemmed | REACTIONS OF RABBITS TO NON-HEMOLYTIC STREPTOCOCCI : I. GENERAL TUBERCULIN-LIKE HYPERSENSITIVENESS, ALLERGY, OR HYPERERGY FOLLOWING THE SECONDARY REACTION. |
title_short | REACTIONS OF RABBITS TO NON-HEMOLYTIC STREPTOCOCCI : I. GENERAL TUBERCULIN-LIKE HYPERSENSITIVENESS, ALLERGY, OR HYPERERGY FOLLOWING THE SECONDARY REACTION. |
title_sort | reactions of rabbits to non-hemolytic streptococci : i. general tuberculin-like hypersensitiveness, allergy, or hyperergy following the secondary reaction. |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131572/ https://www.ncbi.nlm.nih.gov/pubmed/19869568 |
work_keys_str_mv | AT derickcl reactionsofrabbitstononhemolyticstreptococciigeneraltuberculinlikehypersensitivenessallergyorhyperergyfollowingthesecondaryreaction AT swifthomerf reactionsofrabbitstononhemolyticstreptococciigeneraltuberculinlikehypersensitivenessallergyorhyperergyfollowingthesecondaryreaction |