ON THE MECHANISM OF OPSONIN AND BACTERIOTROPIN ACTION : II. CORRELATION BETWEEN CHANGES IN BACTERIAL SURFACE PROPERTIES AND IN PHAGOCYTOSIS CAUSED BY NORMAL AND IMMUNE SERA.

The work reported in this and in previous papers (1, 7) demonstrates the following relations for acid-fast bacteria and rabbit polymorphonudear leucocytes: 1. The combination of a substance or substances present in fresh immune rabbit serum, heated or unheated, or in fresh unheated normal rabbit ser...

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Detalles Bibliográficos
Autores principales: Lucké, Balduin, McCutcheon, Morton, Strumia, Max, Mudd, Stuart
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1929
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131585/
https://www.ncbi.nlm.nih.gov/pubmed/19869583
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author Lucké, Balduin
McCutcheon, Morton
Strumia, Max
Mudd, Stuart
author_facet Lucké, Balduin
McCutcheon, Morton
Strumia, Max
Mudd, Stuart
author_sort Lucké, Balduin
collection PubMed
description The work reported in this and in previous papers (1, 7) demonstrates the following relations for acid-fast bacteria and rabbit polymorphonudear leucocytes: 1. The combination of a substance or substances present in fresh immune rabbit serum, heated or unheated, or in fresh unheated normal rabbit serum, with a substance or substances in the bacterial surface causes an increase in cohesiveness, decrease in surface potential difference and characteristic alteration in wetting properties of the bacteria, and prepares the bacteria for phagocytosis. 2. (a) The effective substance or substances in the serum may become so altered as the result of heating or aging that combination with the bacterial surface, while causing changes in bacterial surface properties indistinguishable by the present physical-chemical tests from these just mentioned, may not lead to phagocytosis, or may lead to phagocytosis with a prezone not paralleled by a prezone in the changes in surface properties. (b) Sensitization of bacteria with human sera causes changes in surface properties similar to those caused by rabbit sera, but does not lead to phagocytosis by rabbit leucocytes. The spreading requirements of rabbit polymorphonuclear leucocytes are evidently highly selective.
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spelling pubmed-21315852008-04-18 ON THE MECHANISM OF OPSONIN AND BACTERIOTROPIN ACTION : II. CORRELATION BETWEEN CHANGES IN BACTERIAL SURFACE PROPERTIES AND IN PHAGOCYTOSIS CAUSED BY NORMAL AND IMMUNE SERA. Lucké, Balduin McCutcheon, Morton Strumia, Max Mudd, Stuart J Exp Med Article The work reported in this and in previous papers (1, 7) demonstrates the following relations for acid-fast bacteria and rabbit polymorphonudear leucocytes: 1. The combination of a substance or substances present in fresh immune rabbit serum, heated or unheated, or in fresh unheated normal rabbit serum, with a substance or substances in the bacterial surface causes an increase in cohesiveness, decrease in surface potential difference and characteristic alteration in wetting properties of the bacteria, and prepares the bacteria for phagocytosis. 2. (a) The effective substance or substances in the serum may become so altered as the result of heating or aging that combination with the bacterial surface, while causing changes in bacterial surface properties indistinguishable by the present physical-chemical tests from these just mentioned, may not lead to phagocytosis, or may lead to phagocytosis with a prezone not paralleled by a prezone in the changes in surface properties. (b) Sensitization of bacteria with human sera causes changes in surface properties similar to those caused by rabbit sera, but does not lead to phagocytosis by rabbit leucocytes. The spreading requirements of rabbit polymorphonuclear leucocytes are evidently highly selective. The Rockefeller University Press 1929-04-30 /pmc/articles/PMC2131585/ /pubmed/19869583 Text en Copyright © Copyright, 1929, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Lucké, Balduin
McCutcheon, Morton
Strumia, Max
Mudd, Stuart
ON THE MECHANISM OF OPSONIN AND BACTERIOTROPIN ACTION : II. CORRELATION BETWEEN CHANGES IN BACTERIAL SURFACE PROPERTIES AND IN PHAGOCYTOSIS CAUSED BY NORMAL AND IMMUNE SERA.
title ON THE MECHANISM OF OPSONIN AND BACTERIOTROPIN ACTION : II. CORRELATION BETWEEN CHANGES IN BACTERIAL SURFACE PROPERTIES AND IN PHAGOCYTOSIS CAUSED BY NORMAL AND IMMUNE SERA.
title_full ON THE MECHANISM OF OPSONIN AND BACTERIOTROPIN ACTION : II. CORRELATION BETWEEN CHANGES IN BACTERIAL SURFACE PROPERTIES AND IN PHAGOCYTOSIS CAUSED BY NORMAL AND IMMUNE SERA.
title_fullStr ON THE MECHANISM OF OPSONIN AND BACTERIOTROPIN ACTION : II. CORRELATION BETWEEN CHANGES IN BACTERIAL SURFACE PROPERTIES AND IN PHAGOCYTOSIS CAUSED BY NORMAL AND IMMUNE SERA.
title_full_unstemmed ON THE MECHANISM OF OPSONIN AND BACTERIOTROPIN ACTION : II. CORRELATION BETWEEN CHANGES IN BACTERIAL SURFACE PROPERTIES AND IN PHAGOCYTOSIS CAUSED BY NORMAL AND IMMUNE SERA.
title_short ON THE MECHANISM OF OPSONIN AND BACTERIOTROPIN ACTION : II. CORRELATION BETWEEN CHANGES IN BACTERIAL SURFACE PROPERTIES AND IN PHAGOCYTOSIS CAUSED BY NORMAL AND IMMUNE SERA.
title_sort on the mechanism of opsonin and bacteriotropin action : ii. correlation between changes in bacterial surface properties and in phagocytosis caused by normal and immune sera.
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131585/
https://www.ncbi.nlm.nih.gov/pubmed/19869583
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