ON THE MECHANISM OF OPSONIN AND BACTERIOTROPIN ACTION : I. CORRELATION BETWEEN CHANGES IN BACTERIAL SURFACE PROPERTIES AND IN PHAGOCYTOSIS CAUSED BY SERA OF ANIMALS UNDER IMMUNIZATION.

Methods are described for investigating the relation between phagocytosis of bacteria by polymorphonuclear leucocytes, and certain physical-chemical properties of the bacterial surface. Serum sensitization causes the following changes in the properties of acid-fast bacteria: (a) increased cohesivene...

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Detalles Bibliográficos
Autores principales: Mudd, Stuart, Lucké, Balduin, McCutcheon, Morton, Strumia, Max
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1929
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131589/
https://www.ncbi.nlm.nih.gov/pubmed/19869582
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author Mudd, Stuart
Lucké, Balduin
McCutcheon, Morton
Strumia, Max
author_facet Mudd, Stuart
Lucké, Balduin
McCutcheon, Morton
Strumia, Max
author_sort Mudd, Stuart
collection PubMed
description Methods are described for investigating the relation between phagocytosis of bacteria by polymorphonuclear leucocytes, and certain physical-chemical properties of the bacterial surface. Serum sensitization causes the following changes in the properties of acid-fast bacteria: (a) increased cohesiveness, (b) decrease in surface electric potential difference, (c) decrease in wettability of the bacteria by oil, and (d) increased phagocytosis. Tests have been conducted periodically with the sera of 4 rabbits under active immunization with as many strains of acid-fast bacteria; the parallelism between the alteration in bacterial surface properties and the promotion of phagocytosis by these sera has been, within the experimental error, complete. The percentage of phagocytosis of a given bacterial suspension has been found to depend both upon the sensitizing serum component or components deposited upon the bacterium and upon the intrinsic properties of the unsensitized bacterial surface.
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spelling pubmed-21315892008-04-18 ON THE MECHANISM OF OPSONIN AND BACTERIOTROPIN ACTION : I. CORRELATION BETWEEN CHANGES IN BACTERIAL SURFACE PROPERTIES AND IN PHAGOCYTOSIS CAUSED BY SERA OF ANIMALS UNDER IMMUNIZATION. Mudd, Stuart Lucké, Balduin McCutcheon, Morton Strumia, Max J Exp Med Article Methods are described for investigating the relation between phagocytosis of bacteria by polymorphonuclear leucocytes, and certain physical-chemical properties of the bacterial surface. Serum sensitization causes the following changes in the properties of acid-fast bacteria: (a) increased cohesiveness, (b) decrease in surface electric potential difference, (c) decrease in wettability of the bacteria by oil, and (d) increased phagocytosis. Tests have been conducted periodically with the sera of 4 rabbits under active immunization with as many strains of acid-fast bacteria; the parallelism between the alteration in bacterial surface properties and the promotion of phagocytosis by these sera has been, within the experimental error, complete. The percentage of phagocytosis of a given bacterial suspension has been found to depend both upon the sensitizing serum component or components deposited upon the bacterium and upon the intrinsic properties of the unsensitized bacterial surface. The Rockefeller University Press 1929-04-30 /pmc/articles/PMC2131589/ /pubmed/19869582 Text en Copyright © Copyright, 1929, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Mudd, Stuart
Lucké, Balduin
McCutcheon, Morton
Strumia, Max
ON THE MECHANISM OF OPSONIN AND BACTERIOTROPIN ACTION : I. CORRELATION BETWEEN CHANGES IN BACTERIAL SURFACE PROPERTIES AND IN PHAGOCYTOSIS CAUSED BY SERA OF ANIMALS UNDER IMMUNIZATION.
title ON THE MECHANISM OF OPSONIN AND BACTERIOTROPIN ACTION : I. CORRELATION BETWEEN CHANGES IN BACTERIAL SURFACE PROPERTIES AND IN PHAGOCYTOSIS CAUSED BY SERA OF ANIMALS UNDER IMMUNIZATION.
title_full ON THE MECHANISM OF OPSONIN AND BACTERIOTROPIN ACTION : I. CORRELATION BETWEEN CHANGES IN BACTERIAL SURFACE PROPERTIES AND IN PHAGOCYTOSIS CAUSED BY SERA OF ANIMALS UNDER IMMUNIZATION.
title_fullStr ON THE MECHANISM OF OPSONIN AND BACTERIOTROPIN ACTION : I. CORRELATION BETWEEN CHANGES IN BACTERIAL SURFACE PROPERTIES AND IN PHAGOCYTOSIS CAUSED BY SERA OF ANIMALS UNDER IMMUNIZATION.
title_full_unstemmed ON THE MECHANISM OF OPSONIN AND BACTERIOTROPIN ACTION : I. CORRELATION BETWEEN CHANGES IN BACTERIAL SURFACE PROPERTIES AND IN PHAGOCYTOSIS CAUSED BY SERA OF ANIMALS UNDER IMMUNIZATION.
title_short ON THE MECHANISM OF OPSONIN AND BACTERIOTROPIN ACTION : I. CORRELATION BETWEEN CHANGES IN BACTERIAL SURFACE PROPERTIES AND IN PHAGOCYTOSIS CAUSED BY SERA OF ANIMALS UNDER IMMUNIZATION.
title_sort on the mechanism of opsonin and bacteriotropin action : i. correlation between changes in bacterial surface properties and in phagocytosis caused by sera of animals under immunization.
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131589/
https://www.ncbi.nlm.nih.gov/pubmed/19869582
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