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IMMUNOLOGICAL STUDIES IN RELATION TO THE SUPRARENAL GLAND : V. THE EFFECT OF REPEATED INJECTIONS OF SOLUTIONS CONTAINING SODIUM SALTS AND GLUCOSE ON THE HEMOLYSIN FORMATION OF NORMAL AND SUPRARENALECTOMIZED RATS
Table I and Figs. 1 and 2 summarize the experiments done on 150 rats. Suprarenalectomy in rats is followed by a striking depression in antibody formation most marked during the first week following the operation. Repeated injections of large amounts of isotonic sodium chloride or sodium acetate solu...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1929
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131606/ https://www.ncbi.nlm.nih.gov/pubmed/19869609 |
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author | Marmorston-Gottesman, J. Perla, David |
author_facet | Marmorston-Gottesman, J. Perla, David |
author_sort | Marmorston-Gottesman, J. |
collection | PubMed |
description | Table I and Figs. 1 and 2 summarize the experiments done on 150 rats. Suprarenalectomy in rats is followed by a striking depression in antibody formation most marked during the first week following the operation. Repeated injections of large amounts of isotonic sodium chloride or sodium acetate solutions restore the antibody titer to normal. The effect of these solutions is not due to diuresis alone, since isotonic glucose solution does not affect the titer, nor to the sodium alone, since hypertonic solutions of sodium chloride in small volume have little influence on the titer. Both the sodium ion and the water volume are necessary in the restoration of the titer. |
format | Text |
id | pubmed-2131606 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1929 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21316062008-04-18 IMMUNOLOGICAL STUDIES IN RELATION TO THE SUPRARENAL GLAND : V. THE EFFECT OF REPEATED INJECTIONS OF SOLUTIONS CONTAINING SODIUM SALTS AND GLUCOSE ON THE HEMOLYSIN FORMATION OF NORMAL AND SUPRARENALECTOMIZED RATS Marmorston-Gottesman, J. Perla, David J Exp Med Article Table I and Figs. 1 and 2 summarize the experiments done on 150 rats. Suprarenalectomy in rats is followed by a striking depression in antibody formation most marked during the first week following the operation. Repeated injections of large amounts of isotonic sodium chloride or sodium acetate solutions restore the antibody titer to normal. The effect of these solutions is not due to diuresis alone, since isotonic glucose solution does not affect the titer, nor to the sodium alone, since hypertonic solutions of sodium chloride in small volume have little influence on the titer. Both the sodium ion and the water volume are necessary in the restoration of the titer. The Rockefeller University Press 1929-06-30 /pmc/articles/PMC2131606/ /pubmed/19869609 Text en Copyright © Copyright, 1929, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Marmorston-Gottesman, J. Perla, David IMMUNOLOGICAL STUDIES IN RELATION TO THE SUPRARENAL GLAND : V. THE EFFECT OF REPEATED INJECTIONS OF SOLUTIONS CONTAINING SODIUM SALTS AND GLUCOSE ON THE HEMOLYSIN FORMATION OF NORMAL AND SUPRARENALECTOMIZED RATS |
title | IMMUNOLOGICAL STUDIES IN RELATION TO THE SUPRARENAL GLAND : V. THE EFFECT OF REPEATED INJECTIONS OF SOLUTIONS CONTAINING SODIUM SALTS AND GLUCOSE ON THE HEMOLYSIN FORMATION OF NORMAL AND SUPRARENALECTOMIZED RATS |
title_full | IMMUNOLOGICAL STUDIES IN RELATION TO THE SUPRARENAL GLAND : V. THE EFFECT OF REPEATED INJECTIONS OF SOLUTIONS CONTAINING SODIUM SALTS AND GLUCOSE ON THE HEMOLYSIN FORMATION OF NORMAL AND SUPRARENALECTOMIZED RATS |
title_fullStr | IMMUNOLOGICAL STUDIES IN RELATION TO THE SUPRARENAL GLAND : V. THE EFFECT OF REPEATED INJECTIONS OF SOLUTIONS CONTAINING SODIUM SALTS AND GLUCOSE ON THE HEMOLYSIN FORMATION OF NORMAL AND SUPRARENALECTOMIZED RATS |
title_full_unstemmed | IMMUNOLOGICAL STUDIES IN RELATION TO THE SUPRARENAL GLAND : V. THE EFFECT OF REPEATED INJECTIONS OF SOLUTIONS CONTAINING SODIUM SALTS AND GLUCOSE ON THE HEMOLYSIN FORMATION OF NORMAL AND SUPRARENALECTOMIZED RATS |
title_short | IMMUNOLOGICAL STUDIES IN RELATION TO THE SUPRARENAL GLAND : V. THE EFFECT OF REPEATED INJECTIONS OF SOLUTIONS CONTAINING SODIUM SALTS AND GLUCOSE ON THE HEMOLYSIN FORMATION OF NORMAL AND SUPRARENALECTOMIZED RATS |
title_sort | immunological studies in relation to the suprarenal gland : v. the effect of repeated injections of solutions containing sodium salts and glucose on the hemolysin formation of normal and suprarenalectomized rats |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131606/ https://www.ncbi.nlm.nih.gov/pubmed/19869609 |
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