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ON THE RELATION OF BACTERIA TO SO-CALLED "CHEMICAL PNEUMONIA"

The question of a causal relation of the bacteria in gassed lungs to the pneumonia present cannot be regarded as decided. It may be said that: 1. The appearance of gassed lungs with pneumonia is very similar to the pneumonia of known bacterial origin. 2. In a few cases the type of pneumonia found co...

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Autores principales: Koontz, A. R., Allen, M. S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1929
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131609/
https://www.ncbi.nlm.nih.gov/pubmed/19869606
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author Koontz, A. R.
Allen, M. S.
author_facet Koontz, A. R.
Allen, M. S.
author_sort Koontz, A. R.
collection PubMed
description The question of a causal relation of the bacteria in gassed lungs to the pneumonia present cannot be regarded as decided. It may be said that: 1. The appearance of gassed lungs with pneumonia is very similar to the pneumonia of known bacterial origin. 2. In a few cases the type of pneumonia found coincides with the reported cases of so-called "chemical pneumonia," which is characterized by a preponderance of epithelial cells in the exudate. 3. Gassed lungs are not sterile but show highly varying numbers of bacteria. 4. The bacteria are not intracellular and are not present in large numbers in the majority of cases. The arguments for and against a causal relationship between the bacteria and the pneumonia may be summed up as follows: 1. Against a Causal Relationship a. The early appearance of pneumonia after gassing. b. The occurrence of pneumonia with very small numbers of bacteria present. c. The fact that very few bacteria are engulfed by leucocytes in gassed lungs, whereas large numbers are present in the non-gassed pneumonias and are conspicuously intracellular. 2. In Favor of a Causal Relationship a. The presence of bacteria in any numbers. b. The picture of broncho-pneumonia presented is similar to broncho-pneumonia of known bacterial origin. c. Pneumonias characterized by large numbers of epithelial cells in the exudate (so-called "chemical pneumonia") occur in animals that were never gassed or subjected to other irritating substances in any way.
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spelling pubmed-21316092008-04-18 ON THE RELATION OF BACTERIA TO SO-CALLED "CHEMICAL PNEUMONIA" Koontz, A. R. Allen, M. S. J Exp Med Article The question of a causal relation of the bacteria in gassed lungs to the pneumonia present cannot be regarded as decided. It may be said that: 1. The appearance of gassed lungs with pneumonia is very similar to the pneumonia of known bacterial origin. 2. In a few cases the type of pneumonia found coincides with the reported cases of so-called "chemical pneumonia," which is characterized by a preponderance of epithelial cells in the exudate. 3. Gassed lungs are not sterile but show highly varying numbers of bacteria. 4. The bacteria are not intracellular and are not present in large numbers in the majority of cases. The arguments for and against a causal relationship between the bacteria and the pneumonia may be summed up as follows: 1. Against a Causal Relationship a. The early appearance of pneumonia after gassing. b. The occurrence of pneumonia with very small numbers of bacteria present. c. The fact that very few bacteria are engulfed by leucocytes in gassed lungs, whereas large numbers are present in the non-gassed pneumonias and are conspicuously intracellular. 2. In Favor of a Causal Relationship a. The presence of bacteria in any numbers. b. The picture of broncho-pneumonia presented is similar to broncho-pneumonia of known bacterial origin. c. Pneumonias characterized by large numbers of epithelial cells in the exudate (so-called "chemical pneumonia") occur in animals that were never gassed or subjected to other irritating substances in any way. The Rockefeller University Press 1929-06-30 /pmc/articles/PMC2131609/ /pubmed/19869606 Text en Copyright © Copyright, 1929, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Koontz, A. R.
Allen, M. S.
ON THE RELATION OF BACTERIA TO SO-CALLED "CHEMICAL PNEUMONIA"
title ON THE RELATION OF BACTERIA TO SO-CALLED "CHEMICAL PNEUMONIA"
title_full ON THE RELATION OF BACTERIA TO SO-CALLED "CHEMICAL PNEUMONIA"
title_fullStr ON THE RELATION OF BACTERIA TO SO-CALLED "CHEMICAL PNEUMONIA"
title_full_unstemmed ON THE RELATION OF BACTERIA TO SO-CALLED "CHEMICAL PNEUMONIA"
title_short ON THE RELATION OF BACTERIA TO SO-CALLED "CHEMICAL PNEUMONIA"
title_sort on the relation of bacteria to so-called "chemical pneumonia"
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131609/
https://www.ncbi.nlm.nih.gov/pubmed/19869606
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