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STUDIES OF TISSUE MAINTENANCE : II. THE SERVICE TO THE LIVER AND DIGESTIVE TRACT AFTER HEMORRHAGE

The vascular readjustments in compensation for a greatly reduced blood bulk affect the service rendered by the blood to the gastrointestinal tract and liver far less than they do that to the skin and muscles. Into these latter tissues india ink is carried almost not at all, whereas it circulates in...

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Autor principal: Gilding, H. P.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1929
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131620/
https://www.ncbi.nlm.nih.gov/pubmed/19869615
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author Gilding, H. P.
author_facet Gilding, H. P.
author_sort Gilding, H. P.
collection PubMed
description The vascular readjustments in compensation for a greatly reduced blood bulk affect the service rendered by the blood to the gastrointestinal tract and liver far less than they do that to the skin and muscles. Into these latter tissues india ink is carried almost not at all, whereas it circulates in quantity through the capillaries of the bowel and liver. Evidently vaso-constriction is much less effective in these viscera. Nowhere in them does one find a patchy ischemia like that so wide-spread in the peripheral tissues. Blood service is maintained to the same extent everywhere throughout the liver even when one of its two sources (hepatic artery or portal vein) is obstructed, and the intrahepatic blood pressure brought very low. A pronounced patchy ischemia of the stomach and large bowel can be induced by intravenous injection into normal animals of sufficient epinephrin to cause the systemic blood pressure to mount to an abnormally high level. Pituitrin used in the same way has a greater effect; blood service to the organs mentioned may be completely abolished by means of it. In both instances, though, service to the small gut and liver is still excellently and evenly maintained.
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spelling pubmed-21316202008-04-18 STUDIES OF TISSUE MAINTENANCE : II. THE SERVICE TO THE LIVER AND DIGESTIVE TRACT AFTER HEMORRHAGE Gilding, H. P. J Exp Med Article The vascular readjustments in compensation for a greatly reduced blood bulk affect the service rendered by the blood to the gastrointestinal tract and liver far less than they do that to the skin and muscles. Into these latter tissues india ink is carried almost not at all, whereas it circulates in quantity through the capillaries of the bowel and liver. Evidently vaso-constriction is much less effective in these viscera. Nowhere in them does one find a patchy ischemia like that so wide-spread in the peripheral tissues. Blood service is maintained to the same extent everywhere throughout the liver even when one of its two sources (hepatic artery or portal vein) is obstructed, and the intrahepatic blood pressure brought very low. A pronounced patchy ischemia of the stomach and large bowel can be induced by intravenous injection into normal animals of sufficient epinephrin to cause the systemic blood pressure to mount to an abnormally high level. Pituitrin used in the same way has a greater effect; blood service to the organs mentioned may be completely abolished by means of it. In both instances, though, service to the small gut and liver is still excellently and evenly maintained. The Rockefeller University Press 1929-07-31 /pmc/articles/PMC2131620/ /pubmed/19869615 Text en Copyright © Copyright, 1929, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Gilding, H. P.
STUDIES OF TISSUE MAINTENANCE : II. THE SERVICE TO THE LIVER AND DIGESTIVE TRACT AFTER HEMORRHAGE
title STUDIES OF TISSUE MAINTENANCE : II. THE SERVICE TO THE LIVER AND DIGESTIVE TRACT AFTER HEMORRHAGE
title_full STUDIES OF TISSUE MAINTENANCE : II. THE SERVICE TO THE LIVER AND DIGESTIVE TRACT AFTER HEMORRHAGE
title_fullStr STUDIES OF TISSUE MAINTENANCE : II. THE SERVICE TO THE LIVER AND DIGESTIVE TRACT AFTER HEMORRHAGE
title_full_unstemmed STUDIES OF TISSUE MAINTENANCE : II. THE SERVICE TO THE LIVER AND DIGESTIVE TRACT AFTER HEMORRHAGE
title_short STUDIES OF TISSUE MAINTENANCE : II. THE SERVICE TO THE LIVER AND DIGESTIVE TRACT AFTER HEMORRHAGE
title_sort studies of tissue maintenance : ii. the service to the liver and digestive tract after hemorrhage
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131620/
https://www.ncbi.nlm.nih.gov/pubmed/19869615
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