THE LIVER AS THE SOURCE OF FIBRINOGEN

In hepatectomized rabbits a progressive decrease in blood fibrinogen occurs. Partial defibrination in the liverless rabbit invariably results in a progressive decrease in blood fibrinogen preceded by a temporary and slight rise. No evidence has been secured of fibrinogen regeneration in the absence...

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Detalles Bibliográficos
Autores principales: Drury, D. R., McMaster, Philip D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1929
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131651/
https://www.ncbi.nlm.nih.gov/pubmed/19869647
Descripción
Sumario:In hepatectomized rabbits a progressive decrease in blood fibrinogen occurs. Partial defibrination in the liverless rabbit invariably results in a progressive decrease in blood fibrinogen preceded by a temporary and slight rise. No evidence has been secured of fibrinogen regeneration in the absence of the liver. From this it follows that the liver is the essential source of fibrinogen and in all probability the sole one.

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