A Tale of Switched Functions: From Cyclooxygenase Inhibition to M-Channel Modulation in New Diphenylamine Derivatives

Cyclooxygenase (COX) enzymes are molecular targets of nonsteroidal anti-inflammatory drugs (NSAIDs), the most used medication worldwide. However, the COX enzymes are not the sole molecular targets of NSAIDs. Recently, we showed that two NSAIDs, diclofenac and meclofenamate, also act as openers of Kv...

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Detalles Bibliográficos
Autores principales: Peretz, Asher, Degani-Katzav, Nurit, Talmon, Maya, Danieli, Eyal, Gopin, Anna, Malka, Eti, Nachman, Rachel, Raz, Amiram, Shabat, Doron, Attali, Bernard
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131780/
https://www.ncbi.nlm.nih.gov/pubmed/18159230
http://dx.doi.org/10.1371/journal.pone.0001332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131780/
https://www.ncbi.nlm.nih.gov/pubmed/18159230
http://dx.doi.org/10.1371/journal.pone.0001332

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