THE RÔLE OF THE RETICULO-ENDOTHELIAL SYSTEM IN IMMUNITY : VII. THE EFFECT OF LOCAL AND SYSTEMIC BLOCKADE ON THE TOXIC ACTION OF HETEROPHILE (FORSSMAN) SERA IN GUINEA PIGS

1. Guinea pigs blocked by intravenous injection of either India ink or trypan blue succumbed with fatal shock after the intravenous injection of heterophile immune serum, although the time of death was somewhat delayed as compared with normal controls. 2. Local blockade of the skin of guinea pigs wi...

Descripción completa

Detalles Bibliográficos
Autores principales: Jungeblut, Claus W., Newnan, Gladys
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1930
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131807/
https://www.ncbi.nlm.nih.gov/pubmed/19869672
_version_ 1782142299354955776
author Jungeblut, Claus W.
Newnan, Gladys
author_facet Jungeblut, Claus W.
Newnan, Gladys
author_sort Jungeblut, Claus W.
collection PubMed
description 1. Guinea pigs blocked by intravenous injection of either India ink or trypan blue succumbed with fatal shock after the intravenous injection of heterophile immune serum, although the time of death was somewhat delayed as compared with normal controls. 2. Local blockade of the skin of guinea pigs with trypan blue inhibited completely the development of the characteristic skin reaction following intracutaneous injection of Forssman serum within the blocked area. 3. Infiltration of the skin of guinea pigs with India ink afforded no protection against the full development of the toxic skin reaction.
format Text
id pubmed-2131807
institution National Center for Biotechnology Information
language English
publishDate 1930
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21318072008-04-18 THE RÔLE OF THE RETICULO-ENDOTHELIAL SYSTEM IN IMMUNITY : VII. THE EFFECT OF LOCAL AND SYSTEMIC BLOCKADE ON THE TOXIC ACTION OF HETEROPHILE (FORSSMAN) SERA IN GUINEA PIGS Jungeblut, Claus W. Newnan, Gladys J Exp Med Article 1. Guinea pigs blocked by intravenous injection of either India ink or trypan blue succumbed with fatal shock after the intravenous injection of heterophile immune serum, although the time of death was somewhat delayed as compared with normal controls. 2. Local blockade of the skin of guinea pigs with trypan blue inhibited completely the development of the characteristic skin reaction following intracutaneous injection of Forssman serum within the blocked area. 3. Infiltration of the skin of guinea pigs with India ink afforded no protection against the full development of the toxic skin reaction. The Rockefeller University Press 1930-01-01 /pmc/articles/PMC2131807/ /pubmed/19869672 Text en Copyright © Copyright, 1930, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Jungeblut, Claus W.
Newnan, Gladys
THE RÔLE OF THE RETICULO-ENDOTHELIAL SYSTEM IN IMMUNITY : VII. THE EFFECT OF LOCAL AND SYSTEMIC BLOCKADE ON THE TOXIC ACTION OF HETEROPHILE (FORSSMAN) SERA IN GUINEA PIGS
title THE RÔLE OF THE RETICULO-ENDOTHELIAL SYSTEM IN IMMUNITY : VII. THE EFFECT OF LOCAL AND SYSTEMIC BLOCKADE ON THE TOXIC ACTION OF HETEROPHILE (FORSSMAN) SERA IN GUINEA PIGS
title_full THE RÔLE OF THE RETICULO-ENDOTHELIAL SYSTEM IN IMMUNITY : VII. THE EFFECT OF LOCAL AND SYSTEMIC BLOCKADE ON THE TOXIC ACTION OF HETEROPHILE (FORSSMAN) SERA IN GUINEA PIGS
title_fullStr THE RÔLE OF THE RETICULO-ENDOTHELIAL SYSTEM IN IMMUNITY : VII. THE EFFECT OF LOCAL AND SYSTEMIC BLOCKADE ON THE TOXIC ACTION OF HETEROPHILE (FORSSMAN) SERA IN GUINEA PIGS
title_full_unstemmed THE RÔLE OF THE RETICULO-ENDOTHELIAL SYSTEM IN IMMUNITY : VII. THE EFFECT OF LOCAL AND SYSTEMIC BLOCKADE ON THE TOXIC ACTION OF HETEROPHILE (FORSSMAN) SERA IN GUINEA PIGS
title_short THE RÔLE OF THE RETICULO-ENDOTHELIAL SYSTEM IN IMMUNITY : VII. THE EFFECT OF LOCAL AND SYSTEMIC BLOCKADE ON THE TOXIC ACTION OF HETEROPHILE (FORSSMAN) SERA IN GUINEA PIGS
title_sort rôle of the reticulo-endothelial system in immunity : vii. the effect of local and systemic blockade on the toxic action of heterophile (forssman) sera in guinea pigs
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131807/
https://www.ncbi.nlm.nih.gov/pubmed/19869672
work_keys_str_mv AT jungeblutclausw theroleofthereticuloendothelialsysteminimmunityviitheeffectoflocalandsystemicblockadeonthetoxicactionofheterophileforssmanserainguineapigs
AT newnangladys theroleofthereticuloendothelialsysteminimmunityviitheeffectoflocalandsystemicblockadeonthetoxicactionofheterophileforssmanserainguineapigs
AT jungeblutclausw roleofthereticuloendothelialsysteminimmunityviitheeffectoflocalandsystemicblockadeonthetoxicactionofheterophileforssmanserainguineapigs
AT newnangladys roleofthereticuloendothelialsysteminimmunityviitheeffectoflocalandsystemicblockadeonthetoxicactionofheterophileforssmanserainguineapigs

Ejemplares similares