STUDIES ON INFLAMMATION : II. A MEASURE OF THE PERMEABILITY OF CAPILLARIES IN AN INFLAMED AREA

1. By means of a colorimetric method the concentration of trypan blue in capillaries can be estimated by direct observation and its changes followed as the dye passes out of the circulating blood stream. 2. The change in concentration of trypan blue in the capillaries of both the normal and the infl...

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Detalles Bibliográficos
Autores principales: Menkin, Valy, Menkin, Miriam F.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1930
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131811/
https://www.ncbi.nlm.nih.gov/pubmed/19869691
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author Menkin, Valy
Menkin, Miriam F.
author_facet Menkin, Valy
Menkin, Miriam F.
author_sort Menkin, Valy
collection PubMed
description 1. By means of a colorimetric method the concentration of trypan blue in capillaries can be estimated by direct observation and its changes followed as the dye passes out of the circulating blood stream. 2. The change in concentration of trypan blue in the capillaries of both the normal and the inflamed mesentery of frogs can be described by two separate exponential equations of the type: y = be(-ax). 3. From these equations it is found that the rate of fall of concentration following intraventricular injection of the dye is almost twice as great in the capillaries of the inflamed as in those of the normal mesentery. This difference is a measure of increased permeability with inflammation.
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spelling pubmed-21318112008-04-18 STUDIES ON INFLAMMATION : II. A MEASURE OF THE PERMEABILITY OF CAPILLARIES IN AN INFLAMED AREA Menkin, Valy Menkin, Miriam F. J Exp Med Article 1. By means of a colorimetric method the concentration of trypan blue in capillaries can be estimated by direct observation and its changes followed as the dye passes out of the circulating blood stream. 2. The change in concentration of trypan blue in the capillaries of both the normal and the inflamed mesentery of frogs can be described by two separate exponential equations of the type: y = be(-ax). 3. From these equations it is found that the rate of fall of concentration following intraventricular injection of the dye is almost twice as great in the capillaries of the inflamed as in those of the normal mesentery. This difference is a measure of increased permeability with inflammation. The Rockefeller University Press 1930-01-31 /pmc/articles/PMC2131811/ /pubmed/19869691 Text en Copyright © Copyright, 1930, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Menkin, Valy
Menkin, Miriam F.
STUDIES ON INFLAMMATION : II. A MEASURE OF THE PERMEABILITY OF CAPILLARIES IN AN INFLAMED AREA
title STUDIES ON INFLAMMATION : II. A MEASURE OF THE PERMEABILITY OF CAPILLARIES IN AN INFLAMED AREA
title_full STUDIES ON INFLAMMATION : II. A MEASURE OF THE PERMEABILITY OF CAPILLARIES IN AN INFLAMED AREA
title_fullStr STUDIES ON INFLAMMATION : II. A MEASURE OF THE PERMEABILITY OF CAPILLARIES IN AN INFLAMED AREA
title_full_unstemmed STUDIES ON INFLAMMATION : II. A MEASURE OF THE PERMEABILITY OF CAPILLARIES IN AN INFLAMED AREA
title_short STUDIES ON INFLAMMATION : II. A MEASURE OF THE PERMEABILITY OF CAPILLARIES IN AN INFLAMED AREA
title_sort studies on inflammation : ii. a measure of the permeability of capillaries in an inflamed area
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131811/
https://www.ncbi.nlm.nih.gov/pubmed/19869691
work_keys_str_mv AT menkinvaly studiesoninflammationiiameasureofthepermeabilityofcapillariesinaninflamedarea
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