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REACTIONS OF RABBITS TO INTRACUTANEOUS INJECTIONS OF PNEUMOCOCCI AND THEIR PRODUCTS : III. REACTIONS AT THE SITE OF INJECTION
1. Following repeated intracutaneous injections of heat-killed pneumococci rabbits acquire an increased skin reactivity. 2. The increased skin reactivity reaches a maximum after 4 to 6 injections have been made, after which it becomes greatly diminished. 3. The relationship of increased skin reactiv...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1930
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131832/ https://www.ncbi.nlm.nih.gov/pubmed/19869704 |
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author | Julianelle, Louis A. |
author_facet | Julianelle, Louis A. |
author_sort | Julianelle, Louis A. |
collection | PubMed |
description | 1. Following repeated intracutaneous injections of heat-killed pneumococci rabbits acquire an increased skin reactivity. 2. The increased skin reactivity reaches a maximum after 4 to 6 injections have been made, after which it becomes greatly diminished. 3. The relationship of increased skin reactivity to active resistance to infection by Pneumococcus, and to the presence of species-specific antibodies in the blood, is still obscure. 4. The increased skin reactivity is not transferable by serum from a highly reactive to a normal rabbit. 5. After regression of the reaction to the first injection of Pneumococcus into the skin, there frequently follows a recrudescence, or exacerbation, of the reaction. 6. The increased skin reactivity and secondary reactions are incited alike by all types and all forms of Pneumococcus. |
format | Text |
id | pubmed-2131832 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1930 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21318322008-04-18 REACTIONS OF RABBITS TO INTRACUTANEOUS INJECTIONS OF PNEUMOCOCCI AND THEIR PRODUCTS : III. REACTIONS AT THE SITE OF INJECTION Julianelle, Louis A. J Exp Med Article 1. Following repeated intracutaneous injections of heat-killed pneumococci rabbits acquire an increased skin reactivity. 2. The increased skin reactivity reaches a maximum after 4 to 6 injections have been made, after which it becomes greatly diminished. 3. The relationship of increased skin reactivity to active resistance to infection by Pneumococcus, and to the presence of species-specific antibodies in the blood, is still obscure. 4. The increased skin reactivity is not transferable by serum from a highly reactive to a normal rabbit. 5. After regression of the reaction to the first injection of Pneumococcus into the skin, there frequently follows a recrudescence, or exacerbation, of the reaction. 6. The increased skin reactivity and secondary reactions are incited alike by all types and all forms of Pneumococcus. The Rockefeller University Press 1930-02-28 /pmc/articles/PMC2131832/ /pubmed/19869704 Text en Copyright © Copyright, 1930, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Julianelle, Louis A. REACTIONS OF RABBITS TO INTRACUTANEOUS INJECTIONS OF PNEUMOCOCCI AND THEIR PRODUCTS : III. REACTIONS AT THE SITE OF INJECTION |
title | REACTIONS OF RABBITS TO INTRACUTANEOUS INJECTIONS OF PNEUMOCOCCI AND THEIR PRODUCTS : III. REACTIONS AT THE SITE OF INJECTION |
title_full | REACTIONS OF RABBITS TO INTRACUTANEOUS INJECTIONS OF PNEUMOCOCCI AND THEIR PRODUCTS : III. REACTIONS AT THE SITE OF INJECTION |
title_fullStr | REACTIONS OF RABBITS TO INTRACUTANEOUS INJECTIONS OF PNEUMOCOCCI AND THEIR PRODUCTS : III. REACTIONS AT THE SITE OF INJECTION |
title_full_unstemmed | REACTIONS OF RABBITS TO INTRACUTANEOUS INJECTIONS OF PNEUMOCOCCI AND THEIR PRODUCTS : III. REACTIONS AT THE SITE OF INJECTION |
title_short | REACTIONS OF RABBITS TO INTRACUTANEOUS INJECTIONS OF PNEUMOCOCCI AND THEIR PRODUCTS : III. REACTIONS AT THE SITE OF INJECTION |
title_sort | reactions of rabbits to intracutaneous injections of pneumococci and their products : iii. reactions at the site of injection |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131832/ https://www.ncbi.nlm.nih.gov/pubmed/19869704 |
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