REACTIONS OF RABBITS TO NON-HEMOLYTIC STREPTOCOCCI : III. A STUDY OF MODES OF SENSITIZATION

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The most satisfactory method thus far found for the induction and maintenance of a high degree of hypersensitiveness—"allergy," "hyperergy"—against non-hemolytic streptococci consists in the repeated production of small focal lesions with minimal doses of bacteria. After a prelim...

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Detalles Bibliográficos
Autores principales: Derick, C. L., Hitchcock, C. H., Swift, Homer F.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1930
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131870/
https://www.ncbi.nlm.nih.gov/pubmed/19869742
Descripción
Sumario:The most satisfactory method thus far found for the induction and maintenance of a high degree of hypersensitiveness—"allergy," "hyperergy"—against non-hemolytic streptococci consists in the repeated production of small focal lesions with minimal doses of bacteria. After a preliminary sensitizing period of about 2 weeks' duration with either large initial, or small multiple daily inoculations, the later foci need be produced only at 7 to 10 day intervals. Chronicity of low-grade infection appears to be an important factor in the attainment of a high degree of hypersensitiveness.

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