REACTIONS OF RABBITS TO NON-HEMOLYTIC STREPTOCOCCI : III. A STUDY OF MODES OF SENSITIZATION

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The most satisfactory method thus far found for the induction and maintenance of a high degree of hypersensitiveness—"allergy," "hyperergy"—against non-hemolytic streptococci consists in the repeated production of small focal lesions with minimal doses of bacteria. After a prelim...

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Detalles Bibliográficos
Autores principales: Derick, C. L., Hitchcock, C. H., Swift, Homer F.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1930
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131870/
https://www.ncbi.nlm.nih.gov/pubmed/19869742
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author Derick, C. L.
Hitchcock, C. H.
Swift, Homer F.
author_facet Derick, C. L.
Hitchcock, C. H.
Swift, Homer F.
author_sort Derick, C. L.
collection PubMed
description The most satisfactory method thus far found for the induction and maintenance of a high degree of hypersensitiveness—"allergy," "hyperergy"—against non-hemolytic streptococci consists in the repeated production of small focal lesions with minimal doses of bacteria. After a preliminary sensitizing period of about 2 weeks' duration with either large initial, or small multiple daily inoculations, the later foci need be produced only at 7 to 10 day intervals. Chronicity of low-grade infection appears to be an important factor in the attainment of a high degree of hypersensitiveness.
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spelling pubmed-21318702008-04-18 REACTIONS OF RABBITS TO NON-HEMOLYTIC STREPTOCOCCI : III. A STUDY OF MODES OF SENSITIZATION Derick, C. L. Hitchcock, C. H. Swift, Homer F. J Exp Med Article The most satisfactory method thus far found for the induction and maintenance of a high degree of hypersensitiveness—"allergy," "hyperergy"—against non-hemolytic streptococci consists in the repeated production of small focal lesions with minimal doses of bacteria. After a preliminary sensitizing period of about 2 weeks' duration with either large initial, or small multiple daily inoculations, the later foci need be produced only at 7 to 10 day intervals. Chronicity of low-grade infection appears to be an important factor in the attainment of a high degree of hypersensitiveness. The Rockefeller University Press 1930-06-30 /pmc/articles/PMC2131870/ /pubmed/19869742 Text en Copyright © Copyright, 1930, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Derick, C. L.
Hitchcock, C. H.
Swift, Homer F.
REACTIONS OF RABBITS TO NON-HEMOLYTIC STREPTOCOCCI : III. A STUDY OF MODES OF SENSITIZATION
title REACTIONS OF RABBITS TO NON-HEMOLYTIC STREPTOCOCCI : III. A STUDY OF MODES OF SENSITIZATION
title_full REACTIONS OF RABBITS TO NON-HEMOLYTIC STREPTOCOCCI : III. A STUDY OF MODES OF SENSITIZATION
title_fullStr REACTIONS OF RABBITS TO NON-HEMOLYTIC STREPTOCOCCI : III. A STUDY OF MODES OF SENSITIZATION
title_full_unstemmed REACTIONS OF RABBITS TO NON-HEMOLYTIC STREPTOCOCCI : III. A STUDY OF MODES OF SENSITIZATION
title_short REACTIONS OF RABBITS TO NON-HEMOLYTIC STREPTOCOCCI : III. A STUDY OF MODES OF SENSITIZATION
title_sort reactions of rabbits to non-hemolytic streptococci : iii. a study of modes of sensitization
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131870/
https://www.ncbi.nlm.nih.gov/pubmed/19869742
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AT swifthomerf reactionsofrabbitstononhemolyticstreptococciiiiastudyofmodesofsensitization

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