SPECIFIC PRECIPITATION AND MOUSE PROTECTION IN TYPE I ANTIPNEUMOCOCCUS SERA

1. A rapid and simple method is given for the approximate determination of the specifically precipitable protein in Type I antipneumococcus sera. 2. It is shown that a close parallel exists between the specifically precipitable protein and the number of mouse protection units in a wide variety of Ty...

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Detalles Bibliográficos
Autores principales: Heidelberger, Michael, Sia, Richard H. P., Kendall, Forrest E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1930
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131887/
https://www.ncbi.nlm.nih.gov/pubmed/19869781
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author Heidelberger, Michael
Sia, Richard H. P.
Kendall, Forrest E.
author_facet Heidelberger, Michael
Sia, Richard H. P.
Kendall, Forrest E.
author_sort Heidelberger, Michael
collection PubMed
description 1. A rapid and simple method is given for the approximate determination of the specifically precipitable protein in Type I antipneumococcus sera. 2. It is shown that a close parallel exists between the specifically precipitable protein and the number of mouse protection units in a wide variety of Type I antipneumococcus sera. 3. Owing to the consistent results obtained and the rapidity, simplicity, and economy of the method, its use is proposed instead of the mouse protection test as a basis for the titration of standard sera and the comparison of others with a standard. 4. A method is given for conveniently preparing highly purified specific polysaccharide of Type I pneumococcus.
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spelling pubmed-21318872008-04-18 SPECIFIC PRECIPITATION AND MOUSE PROTECTION IN TYPE I ANTIPNEUMOCOCCUS SERA Heidelberger, Michael Sia, Richard H. P. Kendall, Forrest E. J Exp Med Article 1. A rapid and simple method is given for the approximate determination of the specifically precipitable protein in Type I antipneumococcus sera. 2. It is shown that a close parallel exists between the specifically precipitable protein and the number of mouse protection units in a wide variety of Type I antipneumococcus sera. 3. Owing to the consistent results obtained and the rapidity, simplicity, and economy of the method, its use is proposed instead of the mouse protection test as a basis for the titration of standard sera and the comparison of others with a standard. 4. A method is given for conveniently preparing highly purified specific polysaccharide of Type I pneumococcus. The Rockefeller University Press 1930-09-30 /pmc/articles/PMC2131887/ /pubmed/19869781 Text en Copyright © Copyright, 1930, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Heidelberger, Michael
Sia, Richard H. P.
Kendall, Forrest E.
SPECIFIC PRECIPITATION AND MOUSE PROTECTION IN TYPE I ANTIPNEUMOCOCCUS SERA
title SPECIFIC PRECIPITATION AND MOUSE PROTECTION IN TYPE I ANTIPNEUMOCOCCUS SERA
title_full SPECIFIC PRECIPITATION AND MOUSE PROTECTION IN TYPE I ANTIPNEUMOCOCCUS SERA
title_fullStr SPECIFIC PRECIPITATION AND MOUSE PROTECTION IN TYPE I ANTIPNEUMOCOCCUS SERA
title_full_unstemmed SPECIFIC PRECIPITATION AND MOUSE PROTECTION IN TYPE I ANTIPNEUMOCOCCUS SERA
title_short SPECIFIC PRECIPITATION AND MOUSE PROTECTION IN TYPE I ANTIPNEUMOCOCCUS SERA
title_sort specific precipitation and mouse protection in type i antipneumococcus sera
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131887/
https://www.ncbi.nlm.nih.gov/pubmed/19869781
work_keys_str_mv AT heidelbergermichael specificprecipitationandmouseprotectionintypeiantipneumococcussera
AT siarichardhp specificprecipitationandmouseprotectionintypeiantipneumococcussera
AT kendallforreste specificprecipitationandmouseprotectionintypeiantipneumococcussera

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