IMMUNOLOGICAL STUDIES IN RELATION TO THE SUPRARENAL GLAND : VI a. TRYPANOSOMA LEWISI INFECTION IN NORMAL ALBINO RATS VI b. TRYPANOSOMA LEWISI INFECTION IN SUPRARENALECTOMIZED ADULT ALBINO RATS

Bilateral suprarenalectomy in rats lowers the resistance to a subsequent infection with T. lewisi. Almost 70 per cent of these rats die within an average period of 5.8 days after infection. The multiplication of the parasites in the circulating stream is not more considerable than in rats previously...

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Autores principales: Marmorston-Gottesman, J., Perla, David, Vorzimer, Jefferson
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1930
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131898/
https://www.ncbi.nlm.nih.gov/pubmed/19869790
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author Marmorston-Gottesman, J.
Perla, David
Vorzimer, Jefferson
author_facet Marmorston-Gottesman, J.
Perla, David
Vorzimer, Jefferson
author_sort Marmorston-Gottesman, J.
collection PubMed
description Bilateral suprarenalectomy in rats lowers the resistance to a subsequent infection with T. lewisi. Almost 70 per cent of these rats die within an average period of 5.8 days after infection. The multiplication of the parasites in the circulating stream is not more considerable than in rats previously normal nor is the duration of the disease in the surviving rats any longer than in the normal group. Bilateral suprarenalectomy does not prevent the formation of immune substances to the parasites but appears to lower the natural resistance of the rat to the toxic effects of the protozoan infection. The acquired immunity to T. lewisi of normal rats as a result of infection is not broken down by subsequent suprarenalectomy. Unilateral nephrectomy does not affect the course of a subsequent infection with T. lewisi.
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spelling pubmed-21318982008-04-18 IMMUNOLOGICAL STUDIES IN RELATION TO THE SUPRARENAL GLAND : VI a. TRYPANOSOMA LEWISI INFECTION IN NORMAL ALBINO RATS VI b. TRYPANOSOMA LEWISI INFECTION IN SUPRARENALECTOMIZED ADULT ALBINO RATS Marmorston-Gottesman, J. Perla, David Vorzimer, Jefferson J Exp Med Article Bilateral suprarenalectomy in rats lowers the resistance to a subsequent infection with T. lewisi. Almost 70 per cent of these rats die within an average period of 5.8 days after infection. The multiplication of the parasites in the circulating stream is not more considerable than in rats previously normal nor is the duration of the disease in the surviving rats any longer than in the normal group. Bilateral suprarenalectomy does not prevent the formation of immune substances to the parasites but appears to lower the natural resistance of the rat to the toxic effects of the protozoan infection. The acquired immunity to T. lewisi of normal rats as a result of infection is not broken down by subsequent suprarenalectomy. Unilateral nephrectomy does not affect the course of a subsequent infection with T. lewisi. The Rockefeller University Press 1930-09-30 /pmc/articles/PMC2131898/ /pubmed/19869790 Text en Copyright © Copyright, 1930, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Marmorston-Gottesman, J.
Perla, David
Vorzimer, Jefferson
IMMUNOLOGICAL STUDIES IN RELATION TO THE SUPRARENAL GLAND : VI a. TRYPANOSOMA LEWISI INFECTION IN NORMAL ALBINO RATS VI b. TRYPANOSOMA LEWISI INFECTION IN SUPRARENALECTOMIZED ADULT ALBINO RATS
title IMMUNOLOGICAL STUDIES IN RELATION TO THE SUPRARENAL GLAND : VI a. TRYPANOSOMA LEWISI INFECTION IN NORMAL ALBINO RATS VI b. TRYPANOSOMA LEWISI INFECTION IN SUPRARENALECTOMIZED ADULT ALBINO RATS
title_full IMMUNOLOGICAL STUDIES IN RELATION TO THE SUPRARENAL GLAND : VI a. TRYPANOSOMA LEWISI INFECTION IN NORMAL ALBINO RATS VI b. TRYPANOSOMA LEWISI INFECTION IN SUPRARENALECTOMIZED ADULT ALBINO RATS
title_fullStr IMMUNOLOGICAL STUDIES IN RELATION TO THE SUPRARENAL GLAND : VI a. TRYPANOSOMA LEWISI INFECTION IN NORMAL ALBINO RATS VI b. TRYPANOSOMA LEWISI INFECTION IN SUPRARENALECTOMIZED ADULT ALBINO RATS
title_full_unstemmed IMMUNOLOGICAL STUDIES IN RELATION TO THE SUPRARENAL GLAND : VI a. TRYPANOSOMA LEWISI INFECTION IN NORMAL ALBINO RATS VI b. TRYPANOSOMA LEWISI INFECTION IN SUPRARENALECTOMIZED ADULT ALBINO RATS
title_short IMMUNOLOGICAL STUDIES IN RELATION TO THE SUPRARENAL GLAND : VI a. TRYPANOSOMA LEWISI INFECTION IN NORMAL ALBINO RATS VI b. TRYPANOSOMA LEWISI INFECTION IN SUPRARENALECTOMIZED ADULT ALBINO RATS
title_sort immunological studies in relation to the suprarenal gland : vi a. trypanosoma lewisi infection in normal albino rats vi b. trypanosoma lewisi infection in suprarenalectomized adult albino rats
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131898/
https://www.ncbi.nlm.nih.gov/pubmed/19869790
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