THE REACTION OF THE ALBINO RAT TO THE INTRA-AURAL ADMINISTRATION OF CERTAIN BACTERIA ASSOCIATED WITH MIDDLE EAR DISEASE

The infective capacity of three bacteria commonly encountered during a study of natural middle ear disease in a rat colony has been determined by direct intra-aural injection in young rats. One week after the introduction of B. actinoides 75 per cent of the rats showed a purulent exudate in the inje...

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Detalles Bibliográficos
Autor principal: Nelson, John B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1930
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131911/
https://www.ncbi.nlm.nih.gov/pubmed/19869810
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author Nelson, John B.
author_facet Nelson, John B.
author_sort Nelson, John B.
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description The infective capacity of three bacteria commonly encountered during a study of natural middle ear disease in a rat colony has been determined by direct intra-aural injection in young rats. One week after the introduction of B. actinoides 75 per cent of the rats showed a purulent exudate in the injected middle ear cavity and 65 per cent yielded pure cultures of the organism. With hemolytic and non-hemolytic streptococci 75 per cent showed a serous or mucoid exudate and 12 per cent yielded the organism in culture. With a diphtheroid 18 per cent showed a gross reaction in the middle ear which was sterile in every case. The experimental findings are discussed in relation to the etiology of middle ear disease.
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spelling pubmed-21319112008-04-18 THE REACTION OF THE ALBINO RAT TO THE INTRA-AURAL ADMINISTRATION OF CERTAIN BACTERIA ASSOCIATED WITH MIDDLE EAR DISEASE Nelson, John B. J Exp Med Article The infective capacity of three bacteria commonly encountered during a study of natural middle ear disease in a rat colony has been determined by direct intra-aural injection in young rats. One week after the introduction of B. actinoides 75 per cent of the rats showed a purulent exudate in the injected middle ear cavity and 65 per cent yielded pure cultures of the organism. With hemolytic and non-hemolytic streptococci 75 per cent showed a serous or mucoid exudate and 12 per cent yielded the organism in culture. With a diphtheroid 18 per cent showed a gross reaction in the middle ear which was sterile in every case. The experimental findings are discussed in relation to the etiology of middle ear disease. The Rockefeller University Press 1930-11-30 /pmc/articles/PMC2131911/ /pubmed/19869810 Text en Copyright © Copyright, 1930, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Nelson, John B.
THE REACTION OF THE ALBINO RAT TO THE INTRA-AURAL ADMINISTRATION OF CERTAIN BACTERIA ASSOCIATED WITH MIDDLE EAR DISEASE
title THE REACTION OF THE ALBINO RAT TO THE INTRA-AURAL ADMINISTRATION OF CERTAIN BACTERIA ASSOCIATED WITH MIDDLE EAR DISEASE
title_full THE REACTION OF THE ALBINO RAT TO THE INTRA-AURAL ADMINISTRATION OF CERTAIN BACTERIA ASSOCIATED WITH MIDDLE EAR DISEASE
title_fullStr THE REACTION OF THE ALBINO RAT TO THE INTRA-AURAL ADMINISTRATION OF CERTAIN BACTERIA ASSOCIATED WITH MIDDLE EAR DISEASE
title_full_unstemmed THE REACTION OF THE ALBINO RAT TO THE INTRA-AURAL ADMINISTRATION OF CERTAIN BACTERIA ASSOCIATED WITH MIDDLE EAR DISEASE
title_short THE REACTION OF THE ALBINO RAT TO THE INTRA-AURAL ADMINISTRATION OF CERTAIN BACTERIA ASSOCIATED WITH MIDDLE EAR DISEASE
title_sort reaction of the albino rat to the intra-aural administration of certain bacteria associated with middle ear disease
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131911/
https://www.ncbi.nlm.nih.gov/pubmed/19869810
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