THE PRODUCTION OF INFECTION WITH PNEUMOCOCCI IN RABBITS BY INTRADERMAL INOCULATION OF TYPE III PNEUMOCOCCI, THE TREATMENT WITH SPECIFIC ANTISERUM, AND A COMPARISON WITH TYPE I INFECTIONS

Intradermal lesions and subsequent bacteremia were produced in rabbits by the intradermal inoculation of Type III strains freshly isolated from pneumonia cases. Slight intradermal lesions were produced but no bacteremia was found in rabbits inoculated with an old stock Type III strain. The intraderm...

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Detalles Bibliográficos
Autores principales: Watson, Elizabeth L., Cooper, Georgia
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1930
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131915/
https://www.ncbi.nlm.nih.gov/pubmed/19869808
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author Watson, Elizabeth L.
Cooper, Georgia
author_facet Watson, Elizabeth L.
Cooper, Georgia
author_sort Watson, Elizabeth L.
collection PubMed
description Intradermal lesions and subsequent bacteremia were produced in rabbits by the intradermal inoculation of Type III strains freshly isolated from pneumonia cases. Slight intradermal lesions were produced but no bacteremia was found in rabbits inoculated with an old stock Type III strain. The intradermal lesions and the bacteremia produced by the inoculation of Type III cultures in rabbits were usually less severe than those produced by the inoculation of Type I culture. The bacteremia in rabbits was checked and the rabbits protected by suitable amounts of Type III concentrated antiserum given intravenously 24 hours after the infecting dose. The amount of Type III antiserum necessary to protect rabbits inoculated intradermally with virulent Type III cultures was not appreciably greater than the amount of Type I antiserum required to protect against Type I.
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spelling pubmed-21319152008-04-18 THE PRODUCTION OF INFECTION WITH PNEUMOCOCCI IN RABBITS BY INTRADERMAL INOCULATION OF TYPE III PNEUMOCOCCI, THE TREATMENT WITH SPECIFIC ANTISERUM, AND A COMPARISON WITH TYPE I INFECTIONS Watson, Elizabeth L. Cooper, Georgia J Exp Med Article Intradermal lesions and subsequent bacteremia were produced in rabbits by the intradermal inoculation of Type III strains freshly isolated from pneumonia cases. Slight intradermal lesions were produced but no bacteremia was found in rabbits inoculated with an old stock Type III strain. The intradermal lesions and the bacteremia produced by the inoculation of Type III cultures in rabbits were usually less severe than those produced by the inoculation of Type I culture. The bacteremia in rabbits was checked and the rabbits protected by suitable amounts of Type III concentrated antiserum given intravenously 24 hours after the infecting dose. The amount of Type III antiserum necessary to protect rabbits inoculated intradermally with virulent Type III cultures was not appreciably greater than the amount of Type I antiserum required to protect against Type I. The Rockefeller University Press 1930-11-30 /pmc/articles/PMC2131915/ /pubmed/19869808 Text en Copyright © Copyright, 1930, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Watson, Elizabeth L.
Cooper, Georgia
THE PRODUCTION OF INFECTION WITH PNEUMOCOCCI IN RABBITS BY INTRADERMAL INOCULATION OF TYPE III PNEUMOCOCCI, THE TREATMENT WITH SPECIFIC ANTISERUM, AND A COMPARISON WITH TYPE I INFECTIONS
title THE PRODUCTION OF INFECTION WITH PNEUMOCOCCI IN RABBITS BY INTRADERMAL INOCULATION OF TYPE III PNEUMOCOCCI, THE TREATMENT WITH SPECIFIC ANTISERUM, AND A COMPARISON WITH TYPE I INFECTIONS
title_full THE PRODUCTION OF INFECTION WITH PNEUMOCOCCI IN RABBITS BY INTRADERMAL INOCULATION OF TYPE III PNEUMOCOCCI, THE TREATMENT WITH SPECIFIC ANTISERUM, AND A COMPARISON WITH TYPE I INFECTIONS
title_fullStr THE PRODUCTION OF INFECTION WITH PNEUMOCOCCI IN RABBITS BY INTRADERMAL INOCULATION OF TYPE III PNEUMOCOCCI, THE TREATMENT WITH SPECIFIC ANTISERUM, AND A COMPARISON WITH TYPE I INFECTIONS
title_full_unstemmed THE PRODUCTION OF INFECTION WITH PNEUMOCOCCI IN RABBITS BY INTRADERMAL INOCULATION OF TYPE III PNEUMOCOCCI, THE TREATMENT WITH SPECIFIC ANTISERUM, AND A COMPARISON WITH TYPE I INFECTIONS
title_short THE PRODUCTION OF INFECTION WITH PNEUMOCOCCI IN RABBITS BY INTRADERMAL INOCULATION OF TYPE III PNEUMOCOCCI, THE TREATMENT WITH SPECIFIC ANTISERUM, AND A COMPARISON WITH TYPE I INFECTIONS
title_sort production of infection with pneumococci in rabbits by intradermal inoculation of type iii pneumococci, the treatment with specific antiserum, and a comparison with type i infections
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131915/
https://www.ncbi.nlm.nih.gov/pubmed/19869808
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