THE INFLUENCE OF URIC ACID ON THE PERMEABILITY OF MEMBRANES

1. Congo red injected in vivo together with uric acid gives rise to more intense and diffuse red coloring in rats, especially in the subcutaneous and peri-articular tissues, than is the case in control rats injected simply with dye. 2. Uric add added in vitro to solutions of Congo red or trypan blue...

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Detalles Bibliográficos
Autor principal: Chini, Virgilio
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1931
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131947/
https://www.ncbi.nlm.nih.gov/pubmed/19869818
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author Chini, Virgilio
author_facet Chini, Virgilio
author_sort Chini, Virgilio
collection PubMed
description 1. Congo red injected in vivo together with uric acid gives rise to more intense and diffuse red coloring in rats, especially in the subcutaneous and peri-articular tissues, than is the case in control rats injected simply with dye. 2. Uric add added in vitro to solutions of Congo red or trypan blue increases the speed of diffusion of these dyes, both through gelatin and the animal membranes (dialyzers). These results support a view long maintained by Professor Rondoni (25), namely, that some factor of an endothelial-capillary nature must be taken into consideration in manifestations of hyperuricemia and of gout.
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spelling pubmed-21319472008-04-18 THE INFLUENCE OF URIC ACID ON THE PERMEABILITY OF MEMBRANES Chini, Virgilio J Exp Med Article 1. Congo red injected in vivo together with uric acid gives rise to more intense and diffuse red coloring in rats, especially in the subcutaneous and peri-articular tissues, than is the case in control rats injected simply with dye. 2. Uric add added in vitro to solutions of Congo red or trypan blue increases the speed of diffusion of these dyes, both through gelatin and the animal membranes (dialyzers). These results support a view long maintained by Professor Rondoni (25), namely, that some factor of an endothelial-capillary nature must be taken into consideration in manifestations of hyperuricemia and of gout. The Rockefeller University Press 1931-01-01 /pmc/articles/PMC2131947/ /pubmed/19869818 Text en Copyright © Copyright, 1931, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Chini, Virgilio
THE INFLUENCE OF URIC ACID ON THE PERMEABILITY OF MEMBRANES
title THE INFLUENCE OF URIC ACID ON THE PERMEABILITY OF MEMBRANES
title_full THE INFLUENCE OF URIC ACID ON THE PERMEABILITY OF MEMBRANES
title_fullStr THE INFLUENCE OF URIC ACID ON THE PERMEABILITY OF MEMBRANES
title_full_unstemmed THE INFLUENCE OF URIC ACID ON THE PERMEABILITY OF MEMBRANES
title_short THE INFLUENCE OF URIC ACID ON THE PERMEABILITY OF MEMBRANES
title_sort influence of uric acid on the permeability of membranes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131947/
https://www.ncbi.nlm.nih.gov/pubmed/19869818
work_keys_str_mv AT chinivirgilio theinfluenceofuricacidonthepermeabilityofmembranes
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