THE ACTION OF A SPECIFIC ENZYME UPON THE DERMAL INFECTION OF RABBITS WITH TYPE III PNEUMOCOCCUS

The action of the enzyme which specifically decomposes the capsular polysaccharide of Type III Pneumococcus has been tested in Type III pneumococcus dermal infections in rabbits. When injected in sufficient amounts, this enzyme is capable of bringing about a favorable and early termination of the ex...

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Detalles Bibliográficos
Autores principales: Goodner, Kenneth, Dubos, René, Avery, Oswald T.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1932
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132114/
https://www.ncbi.nlm.nih.gov/pubmed/19869998
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author Goodner, Kenneth
Dubos, René
Avery, Oswald T.
author_facet Goodner, Kenneth
Dubos, René
Avery, Oswald T.
author_sort Goodner, Kenneth
collection PubMed
description The action of the enzyme which specifically decomposes the capsular polysaccharide of Type III Pneumococcus has been tested in Type III pneumococcus dermal infections in rabbits. When injected in sufficient amounts, this enzyme is capable of bringing about a favorable and early termination of the experimental disease which ordinarily is fatal in nearly all instances. The results of the present study yield further evidence that the capsular substance is of great importance in pneumococcus infection, since, in so far as known, the only action of which the specific enzyme is capable is that of decomposing the capsular polysaccharide.
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spelling pubmed-21321142008-04-18 THE ACTION OF A SPECIFIC ENZYME UPON THE DERMAL INFECTION OF RABBITS WITH TYPE III PNEUMOCOCCUS Goodner, Kenneth Dubos, René Avery, Oswald T. J Exp Med Article The action of the enzyme which specifically decomposes the capsular polysaccharide of Type III Pneumococcus has been tested in Type III pneumococcus dermal infections in rabbits. When injected in sufficient amounts, this enzyme is capable of bringing about a favorable and early termination of the experimental disease which ordinarily is fatal in nearly all instances. The results of the present study yield further evidence that the capsular substance is of great importance in pneumococcus infection, since, in so far as known, the only action of which the specific enzyme is capable is that of decomposing the capsular polysaccharide. The Rockefeller University Press 1932-02-29 /pmc/articles/PMC2132114/ /pubmed/19869998 Text en Copyright © Copyright, 1932, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Goodner, Kenneth
Dubos, René
Avery, Oswald T.
THE ACTION OF A SPECIFIC ENZYME UPON THE DERMAL INFECTION OF RABBITS WITH TYPE III PNEUMOCOCCUS
title THE ACTION OF A SPECIFIC ENZYME UPON THE DERMAL INFECTION OF RABBITS WITH TYPE III PNEUMOCOCCUS
title_full THE ACTION OF A SPECIFIC ENZYME UPON THE DERMAL INFECTION OF RABBITS WITH TYPE III PNEUMOCOCCUS
title_fullStr THE ACTION OF A SPECIFIC ENZYME UPON THE DERMAL INFECTION OF RABBITS WITH TYPE III PNEUMOCOCCUS
title_full_unstemmed THE ACTION OF A SPECIFIC ENZYME UPON THE DERMAL INFECTION OF RABBITS WITH TYPE III PNEUMOCOCCUS
title_short THE ACTION OF A SPECIFIC ENZYME UPON THE DERMAL INFECTION OF RABBITS WITH TYPE III PNEUMOCOCCUS
title_sort action of a specific enzyme upon the dermal infection of rabbits with type iii pneumococcus
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132114/
https://www.ncbi.nlm.nih.gov/pubmed/19869998
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