PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR : V. ANTIGENIC PROPERTIES OF THE CHICKEN TUMOR I

The injection of tumor extracts and their active protein fractions into rabbits induced the formation of precipitins and neutralizing antibodies. When the major portion of proteins in the tumor extract had been eliminated it induced the formation of neutralizing antibodies, but not of precipitins. T...

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Detalles Bibliográficos
Autores principales: Murphy, James B., Sturm, Ernest, Favilli, Giovanni, Hoffman, Donald C., Claude, Albert
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1932
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132160/
https://www.ncbi.nlm.nih.gov/pubmed/19870048
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author Murphy, James B.
Sturm, Ernest
Favilli, Giovanni
Hoffman, Donald C.
Claude, Albert
author_facet Murphy, James B.
Sturm, Ernest
Favilli, Giovanni
Hoffman, Donald C.
Claude, Albert
author_sort Murphy, James B.
collection PubMed
description The injection of tumor extracts and their active protein fractions into rabbits induced the formation of precipitins and neutralizing antibodies. When the major portion of proteins in the tumor extract had been eliminated it induced the formation of neutralizing antibodies, but not of precipitins. The tumor agent, more highly purified by removal of the viscous fraction, did not induce precipitins, and only 2 out of the 15 sera gave any evidence of neutralizing bodies. After the removal of the major portion of protein, the extracts showed insufficient interaction with the sera to fix complement.
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spelling pubmed-21321602008-04-18 PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR : V. ANTIGENIC PROPERTIES OF THE CHICKEN TUMOR I Murphy, James B. Sturm, Ernest Favilli, Giovanni Hoffman, Donald C. Claude, Albert J Exp Med Article The injection of tumor extracts and their active protein fractions into rabbits induced the formation of precipitins and neutralizing antibodies. When the major portion of proteins in the tumor extract had been eliminated it induced the formation of neutralizing antibodies, but not of precipitins. The tumor agent, more highly purified by removal of the viscous fraction, did not induce precipitins, and only 2 out of the 15 sera gave any evidence of neutralizing bodies. After the removal of the major portion of protein, the extracts showed insufficient interaction with the sera to fix complement. The Rockefeller University Press 1932-06-30 /pmc/articles/PMC2132160/ /pubmed/19870048 Text en Copyright © Copyright, 1932, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Murphy, James B.
Sturm, Ernest
Favilli, Giovanni
Hoffman, Donald C.
Claude, Albert
PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR : V. ANTIGENIC PROPERTIES OF THE CHICKEN TUMOR I
title PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR : V. ANTIGENIC PROPERTIES OF THE CHICKEN TUMOR I
title_full PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR : V. ANTIGENIC PROPERTIES OF THE CHICKEN TUMOR I
title_fullStr PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR : V. ANTIGENIC PROPERTIES OF THE CHICKEN TUMOR I
title_full_unstemmed PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR : V. ANTIGENIC PROPERTIES OF THE CHICKEN TUMOR I
title_short PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR : V. ANTIGENIC PROPERTIES OF THE CHICKEN TUMOR I
title_sort properties of the causative agent of a chicken tumor : v. antigenic properties of the chicken tumor i
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132160/
https://www.ncbi.nlm.nih.gov/pubmed/19870048
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