PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR : III. ATTEMPTS AT ISOLATION OF THE ACTIVE PRINCIPLE

By two methods a protein fraction can be separated out from a Chicken Tumor I extract, which carries all the tumor-producing agent. The precipitate can be dissolved and reprecipitated a number of times without loss of activity. The agent can be largely dissociated from the protein as shown by the fa...

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Detalles Bibliográficos
Autores principales: Murphy, James B., Sturm, Ernest, Claude, Albert, Helmer, Oscar M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1932
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132164/
https://www.ncbi.nlm.nih.gov/pubmed/19870057
Descripción
Sumario:By two methods a protein fraction can be separated out from a Chicken Tumor I extract, which carries all the tumor-producing agent. The precipitate can be dissolved and reprecipitated a number of times without loss of activity. The agent can be largely dissociated from the protein as shown by the fact that aluminum hydroxide will adsorb the protein from an extract and leave the agent behind. This purified material has a very low protein content, if any, as shown by both chemical and biological tests.

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