PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR : III. ATTEMPTS AT ISOLATION OF THE ACTIVE PRINCIPLE

By two methods a protein fraction can be separated out from a Chicken Tumor I extract, which carries all the tumor-producing agent. The precipitate can be dissolved and reprecipitated a number of times without loss of activity. The agent can be largely dissociated from the protein as shown by the fa...

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Detalles Bibliográficos
Autores principales: Murphy, James B., Sturm, Ernest, Claude, Albert, Helmer, Oscar M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1932
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132164/
https://www.ncbi.nlm.nih.gov/pubmed/19870057
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author Murphy, James B.
Sturm, Ernest
Claude, Albert
Helmer, Oscar M.
author_facet Murphy, James B.
Sturm, Ernest
Claude, Albert
Helmer, Oscar M.
author_sort Murphy, James B.
collection PubMed
description By two methods a protein fraction can be separated out from a Chicken Tumor I extract, which carries all the tumor-producing agent. The precipitate can be dissolved and reprecipitated a number of times without loss of activity. The agent can be largely dissociated from the protein as shown by the fact that aluminum hydroxide will adsorb the protein from an extract and leave the agent behind. This purified material has a very low protein content, if any, as shown by both chemical and biological tests.
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spelling pubmed-21321642008-04-18 PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR : III. ATTEMPTS AT ISOLATION OF THE ACTIVE PRINCIPLE Murphy, James B. Sturm, Ernest Claude, Albert Helmer, Oscar M. J Exp Med Article By two methods a protein fraction can be separated out from a Chicken Tumor I extract, which carries all the tumor-producing agent. The precipitate can be dissolved and reprecipitated a number of times without loss of activity. The agent can be largely dissociated from the protein as shown by the fact that aluminum hydroxide will adsorb the protein from an extract and leave the agent behind. This purified material has a very low protein content, if any, as shown by both chemical and biological tests. The Rockefeller University Press 1932-06-30 /pmc/articles/PMC2132164/ /pubmed/19870057 Text en Copyright © Copyright, 1932, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Murphy, James B.
Sturm, Ernest
Claude, Albert
Helmer, Oscar M.
PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR : III. ATTEMPTS AT ISOLATION OF THE ACTIVE PRINCIPLE
title PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR : III. ATTEMPTS AT ISOLATION OF THE ACTIVE PRINCIPLE
title_full PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR : III. ATTEMPTS AT ISOLATION OF THE ACTIVE PRINCIPLE
title_fullStr PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR : III. ATTEMPTS AT ISOLATION OF THE ACTIVE PRINCIPLE
title_full_unstemmed PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR : III. ATTEMPTS AT ISOLATION OF THE ACTIVE PRINCIPLE
title_short PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR : III. ATTEMPTS AT ISOLATION OF THE ACTIVE PRINCIPLE
title_sort properties of the causative agent of a chicken tumor : iii. attempts at isolation of the active principle
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132164/
https://www.ncbi.nlm.nih.gov/pubmed/19870057
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AT helmeroscarm propertiesofthecausativeagentofachickentumoriiiattemptsatisolationoftheactiveprinciple

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