PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR : VI. ACTION OF THE ASSOCIATED INHIBITOR ON MOUSE TUMORS

Water extracts of desiccates of certain relatively slow-growing strains of Chicken Tumors I and X, or the exudates from such tumors, definitely inhibited the growth of a mouse sarcoma (Crocker 180), and were without effect on a mouse carcinoma (Bashford 63) or Mouse Tumor S/37, a rapidly growing sar...

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Detalles Bibliográficos
Autores principales: Murphy, James B., Sturm, Ernest
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1932
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132183/
https://www.ncbi.nlm.nih.gov/pubmed/19870080
Descripción
Sumario:Water extracts of desiccates of certain relatively slow-growing strains of Chicken Tumors I and X, or the exudates from such tumors, definitely inhibited the growth of a mouse sarcoma (Crocker 180), and were without effect on a mouse carcinoma (Bashford 63) or Mouse Tumor S/37, a rapidly growing sarcoma derived from the stroma of a carcinoma. Extensive control tests with extracts from rapidly growing chicken tumors, and from tissues of normal and immune chickens showed no inhibiting action. There was no demonstrable action on the mouse tumors of sera from immunized rabbits, which neutralize the chicken tumor agent, nor of the sera from chickens highly immune to the chicken tumors.

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