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PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR : VI. ACTION OF THE ASSOCIATED INHIBITOR ON MOUSE TUMORS
Water extracts of desiccates of certain relatively slow-growing strains of Chicken Tumors I and X, or the exudates from such tumors, definitely inhibited the growth of a mouse sarcoma (Crocker 180), and were without effect on a mouse carcinoma (Bashford 63) or Mouse Tumor S/37, a rapidly growing sar...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1932
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132183/ https://www.ncbi.nlm.nih.gov/pubmed/19870080 |
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author | Murphy, James B. Sturm, Ernest |
author_facet | Murphy, James B. Sturm, Ernest |
author_sort | Murphy, James B. |
collection | PubMed |
description | Water extracts of desiccates of certain relatively slow-growing strains of Chicken Tumors I and X, or the exudates from such tumors, definitely inhibited the growth of a mouse sarcoma (Crocker 180), and were without effect on a mouse carcinoma (Bashford 63) or Mouse Tumor S/37, a rapidly growing sarcoma derived from the stroma of a carcinoma. Extensive control tests with extracts from rapidly growing chicken tumors, and from tissues of normal and immune chickens showed no inhibiting action. There was no demonstrable action on the mouse tumors of sera from immunized rabbits, which neutralize the chicken tumor agent, nor of the sera from chickens highly immune to the chicken tumors. |
format | Text |
id | pubmed-2132183 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1932 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21321832008-04-18 PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR : VI. ACTION OF THE ASSOCIATED INHIBITOR ON MOUSE TUMORS Murphy, James B. Sturm, Ernest J Exp Med Article Water extracts of desiccates of certain relatively slow-growing strains of Chicken Tumors I and X, or the exudates from such tumors, definitely inhibited the growth of a mouse sarcoma (Crocker 180), and were without effect on a mouse carcinoma (Bashford 63) or Mouse Tumor S/37, a rapidly growing sarcoma derived from the stroma of a carcinoma. Extensive control tests with extracts from rapidly growing chicken tumors, and from tissues of normal and immune chickens showed no inhibiting action. There was no demonstrable action on the mouse tumors of sera from immunized rabbits, which neutralize the chicken tumor agent, nor of the sera from chickens highly immune to the chicken tumors. The Rockefeller University Press 1932-09-30 /pmc/articles/PMC2132183/ /pubmed/19870080 Text en Copyright © Copyright, 1932, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Murphy, James B. Sturm, Ernest PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR : VI. ACTION OF THE ASSOCIATED INHIBITOR ON MOUSE TUMORS |
title | PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR : VI. ACTION OF THE ASSOCIATED INHIBITOR ON MOUSE TUMORS |
title_full | PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR : VI. ACTION OF THE ASSOCIATED INHIBITOR ON MOUSE TUMORS |
title_fullStr | PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR : VI. ACTION OF THE ASSOCIATED INHIBITOR ON MOUSE TUMORS |
title_full_unstemmed | PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR : VI. ACTION OF THE ASSOCIATED INHIBITOR ON MOUSE TUMORS |
title_short | PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR : VI. ACTION OF THE ASSOCIATED INHIBITOR ON MOUSE TUMORS |
title_sort | properties of the causative agent of a chicken tumor : vi. action of the associated inhibitor on mouse tumors |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132183/ https://www.ncbi.nlm.nih.gov/pubmed/19870080 |
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