THE CELLULAR REACTIONS TO LIPOID FRACTIONS FROM ACID-FAST BACILLI

1. A comparative study has been made of the cellular reactions induced by phosphatides from five strains of acid-fast bacilli. Each of these reactions is characterized principally by epithelioid cells and giant cells. 2. The phosphatides are first phagocytized by young connective tissue cells or mon...

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Autores principales: Smithburn, Kenneth C., Sabin, Florence R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1932
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132207/
https://www.ncbi.nlm.nih.gov/pubmed/19870109
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author Smithburn, Kenneth C.
Sabin, Florence R.
author_facet Smithburn, Kenneth C.
Sabin, Florence R.
author_sort Smithburn, Kenneth C.
collection PubMed
description 1. A comparative study has been made of the cellular reactions induced by phosphatides from five strains of acid-fast bacilli. Each of these reactions is characterized principally by epithelioid cells and giant cells. 2. The phosphatides are first phagocytized by young connective tissue cells or monocytes. The lipoid is then dispersed into fine particles with the formation of classical epithelioid cells. 3. A comparison has been made of the reactions induced by heat-killed and defatted tubercle bacilli with those induced by tuberculophosphatide. 4. Further studies have been made to determine whether or not the phosphatide causes sensitization to tuberculin. It does not do so. 5. The life cycle of the epithelioid cell has been observed in all its stages.
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spelling pubmed-21322072008-04-18 THE CELLULAR REACTIONS TO LIPOID FRACTIONS FROM ACID-FAST BACILLI Smithburn, Kenneth C. Sabin, Florence R. J Exp Med Article 1. A comparative study has been made of the cellular reactions induced by phosphatides from five strains of acid-fast bacilli. Each of these reactions is characterized principally by epithelioid cells and giant cells. 2. The phosphatides are first phagocytized by young connective tissue cells or monocytes. The lipoid is then dispersed into fine particles with the formation of classical epithelioid cells. 3. A comparison has been made of the reactions induced by heat-killed and defatted tubercle bacilli with those induced by tuberculophosphatide. 4. Further studies have been made to determine whether or not the phosphatide causes sensitization to tuberculin. It does not do so. 5. The life cycle of the epithelioid cell has been observed in all its stages. The Rockefeller University Press 1932-11-30 /pmc/articles/PMC2132207/ /pubmed/19870109 Text en Copyright © Copyright, 1932, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Smithburn, Kenneth C.
Sabin, Florence R.
THE CELLULAR REACTIONS TO LIPOID FRACTIONS FROM ACID-FAST BACILLI
title THE CELLULAR REACTIONS TO LIPOID FRACTIONS FROM ACID-FAST BACILLI
title_full THE CELLULAR REACTIONS TO LIPOID FRACTIONS FROM ACID-FAST BACILLI
title_fullStr THE CELLULAR REACTIONS TO LIPOID FRACTIONS FROM ACID-FAST BACILLI
title_full_unstemmed THE CELLULAR REACTIONS TO LIPOID FRACTIONS FROM ACID-FAST BACILLI
title_short THE CELLULAR REACTIONS TO LIPOID FRACTIONS FROM ACID-FAST BACILLI
title_sort cellular reactions to lipoid fractions from acid-fast bacilli
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132207/
https://www.ncbi.nlm.nih.gov/pubmed/19870109
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