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THE HYPOPHYSEAL SUBSTANCE GIVING INCREASED GONADOTROPIC EFFECTS WHEN COMBINED WITH PROLAN

The increased gonadotropic effect obtained by combining prolan with hypophyseal extracts can be secured equally well by the use of preparations which contain high amounts of the growth or of the gonad-stimulating hormone. In hypophyseal extracts containing the growth hormone, the synergistic effects...

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Detalles Bibliográficos
Autores principales: Evans, Herbert M., Simpson, Miriam E., Austin, Paul R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1933
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132266/
https://www.ncbi.nlm.nih.gov/pubmed/19870168
Descripción
Sumario:The increased gonadotropic effect obtained by combining prolan with hypophyseal extracts can be secured equally well by the use of preparations which contain high amounts of the growth or of the gonad-stimulating hormone. In hypophyseal extracts containing the growth hormone, the synergistic effects do not parallel the content of growth-promoting substance. Similarly, in hypophyseal extracts containing the gonad-stimulating hormone, the synergistic effects do not parallel the content in the gonadotropic factor. The hypophyseal substance involved has been prepared sufficiently free of the growth and gonad-stimulating hormones to make it inadmissible to consider either of these substances as responsible for the reaction.