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THE EFFECT OF PNEUMOCOCCUS AUTOLYSATES UPON PNEUMOCOCCUS DERMAL INFECTION IN THE RABBIT

In pneumococcus dermal infections in rabbits, the addition of pneumococcus autolysate to an infective inoculum favors the invasiveness of the particular strain employed, but does not alter the kind of virulence possessed by that strain. Autolysates exhibiting this enhancing property also induce purp...

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Detalles Bibliográficos
Autor principal: Goodner, Kenneth
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1933
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132291/
https://www.ncbi.nlm.nih.gov/pubmed/19870186
Descripción
Sumario:In pneumococcus dermal infections in rabbits, the addition of pneumococcus autolysate to an infective inoculum favors the invasiveness of the particular strain employed, but does not alter the kind of virulence possessed by that strain. Autolysates exhibiting this enhancing property also induce purpura in mice and inhibit the coagulation of rabbit blood. The relation of these properties to the infectivity of Pneumococcus and the possible role of bacterial autolysis in natural infection are discussed.