QUANTITATIVE STUDIES ON THE PRECIPITIN REACTION : THE RÔLE OF MULTIPLE REACTIVE GROUPS IN ANTIGEN-ANTIBODY UNION AS ILLUSTRATED BY AN INSTANCE OF CROSS-PRECIPITATION

1. Antisera to R-salt-azo-benzidine-azo-crystalline egg albumin give precipitates with crystalline egg albumin by virtue of their antidye content. 2. The quantitative course of the reactions with increasing amounts of antigen is very similar for the dye-antidye and egg albumin-anti-egg albumin syste...

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Detalles Bibliográficos
Autores principales: Heidelberger, Michael, Kendall, Forrest E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1934
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132333/
https://www.ncbi.nlm.nih.gov/pubmed/19870263
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author Heidelberger, Michael
Kendall, Forrest E.
author_facet Heidelberger, Michael
Kendall, Forrest E.
author_sort Heidelberger, Michael
collection PubMed
description 1. Antisera to R-salt-azo-benzidine-azo-crystalline egg albumin give precipitates with crystalline egg albumin by virtue of their antidye content. 2. The quantitative course of the reactions with increasing amounts of antigen is very similar for the dye-antidye and egg albumin-anti-egg albumin systems, but differs markedly for the cross reaction between egg albumin and antidye. 3. A possible explanation for the occurrence of this one-sided crossreaction is given in terms of reactive groupings on the antigen and antibody. 4. A qualitative expression of the course of the cross-reaction is given in terms of the laws of classical chemistry.
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spelling pubmed-21323332008-04-18 QUANTITATIVE STUDIES ON THE PRECIPITIN REACTION : THE RÔLE OF MULTIPLE REACTIVE GROUPS IN ANTIGEN-ANTIBODY UNION AS ILLUSTRATED BY AN INSTANCE OF CROSS-PRECIPITATION Heidelberger, Michael Kendall, Forrest E. J Exp Med Article 1. Antisera to R-salt-azo-benzidine-azo-crystalline egg albumin give precipitates with crystalline egg albumin by virtue of their antidye content. 2. The quantitative course of the reactions with increasing amounts of antigen is very similar for the dye-antidye and egg albumin-anti-egg albumin systems, but differs markedly for the cross reaction between egg albumin and antidye. 3. A possible explanation for the occurrence of this one-sided crossreaction is given in terms of reactive groupings on the antigen and antibody. 4. A qualitative expression of the course of the cross-reaction is given in terms of the laws of classical chemistry. The Rockefeller University Press 1934-03-31 /pmc/articles/PMC2132333/ /pubmed/19870263 Text en Copyright © Copyright, 1934, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Heidelberger, Michael
Kendall, Forrest E.
QUANTITATIVE STUDIES ON THE PRECIPITIN REACTION : THE RÔLE OF MULTIPLE REACTIVE GROUPS IN ANTIGEN-ANTIBODY UNION AS ILLUSTRATED BY AN INSTANCE OF CROSS-PRECIPITATION
title QUANTITATIVE STUDIES ON THE PRECIPITIN REACTION : THE RÔLE OF MULTIPLE REACTIVE GROUPS IN ANTIGEN-ANTIBODY UNION AS ILLUSTRATED BY AN INSTANCE OF CROSS-PRECIPITATION
title_full QUANTITATIVE STUDIES ON THE PRECIPITIN REACTION : THE RÔLE OF MULTIPLE REACTIVE GROUPS IN ANTIGEN-ANTIBODY UNION AS ILLUSTRATED BY AN INSTANCE OF CROSS-PRECIPITATION
title_fullStr QUANTITATIVE STUDIES ON THE PRECIPITIN REACTION : THE RÔLE OF MULTIPLE REACTIVE GROUPS IN ANTIGEN-ANTIBODY UNION AS ILLUSTRATED BY AN INSTANCE OF CROSS-PRECIPITATION
title_full_unstemmed QUANTITATIVE STUDIES ON THE PRECIPITIN REACTION : THE RÔLE OF MULTIPLE REACTIVE GROUPS IN ANTIGEN-ANTIBODY UNION AS ILLUSTRATED BY AN INSTANCE OF CROSS-PRECIPITATION
title_short QUANTITATIVE STUDIES ON THE PRECIPITIN REACTION : THE RÔLE OF MULTIPLE REACTIVE GROUPS IN ANTIGEN-ANTIBODY UNION AS ILLUSTRATED BY AN INSTANCE OF CROSS-PRECIPITATION
title_sort quantitative studies on the precipitin reaction : the rôle of multiple reactive groups in antigen-antibody union as illustrated by an instance of cross-precipitation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132333/
https://www.ncbi.nlm.nih.gov/pubmed/19870263
work_keys_str_mv AT heidelbergermichael quantitativestudiesontheprecipitinreactiontheroleofmultiplereactivegroupsinantigenantibodyunionasillustratedbyaninstanceofcrossprecipitation
AT kendallforreste quantitativestudiesontheprecipitinreactiontheroleofmultiplereactivegroupsinantigenantibodyunionasillustratedbyaninstanceofcrossprecipitation

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