THE METABOLISM OF COPPER AND IRON IN SPLENECTOMIZED RATS FREE FROM BARTONELLA MURIS INFECTION

Removal of the spleen in albino rats free from Bartonella muris infection is followed by an increased elimination of copper in the feces, which commences 2 weeks after splenectomy. This is associated with a persistent negative copper balance. An increased retention of iron occurs during a period of...

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Detalles Bibliográficos
Autores principales: Sandberg, Marta, Perla, David
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1934
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132417/
https://www.ncbi.nlm.nih.gov/pubmed/19870310
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author Sandberg, Marta
Perla, David
author_facet Sandberg, Marta
Perla, David
author_sort Sandberg, Marta
collection PubMed
description Removal of the spleen in albino rats free from Bartonella muris infection is followed by an increased elimination of copper in the feces, which commences 2 weeks after splenectomy. This is associated with a persistent negative copper balance. An increased retention of iron occurs during a period of 4 to 6 weeks after splenectomy with a return of the iron metabolism to normal after this period. No disturbance in creatine or creatinine metabolism occurs. The uric acid amount is unchanged. There is an increase in the retention of nitrogen, which is first noted 3 weeks after splenectomy. The spleen is essential for the utilization of copper in the body.
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spelling pubmed-21324172008-04-18 THE METABOLISM OF COPPER AND IRON IN SPLENECTOMIZED RATS FREE FROM BARTONELLA MURIS INFECTION Sandberg, Marta Perla, David J Exp Med Article Removal of the spleen in albino rats free from Bartonella muris infection is followed by an increased elimination of copper in the feces, which commences 2 weeks after splenectomy. This is associated with a persistent negative copper balance. An increased retention of iron occurs during a period of 4 to 6 weeks after splenectomy with a return of the iron metabolism to normal after this period. No disturbance in creatine or creatinine metabolism occurs. The uric acid amount is unchanged. There is an increase in the retention of nitrogen, which is first noted 3 weeks after splenectomy. The spleen is essential for the utilization of copper in the body. The Rockefeller University Press 1934-08-31 /pmc/articles/PMC2132417/ /pubmed/19870310 Text en Copyright © Copyright, 1934, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Sandberg, Marta
Perla, David
THE METABOLISM OF COPPER AND IRON IN SPLENECTOMIZED RATS FREE FROM BARTONELLA MURIS INFECTION
title THE METABOLISM OF COPPER AND IRON IN SPLENECTOMIZED RATS FREE FROM BARTONELLA MURIS INFECTION
title_full THE METABOLISM OF COPPER AND IRON IN SPLENECTOMIZED RATS FREE FROM BARTONELLA MURIS INFECTION
title_fullStr THE METABOLISM OF COPPER AND IRON IN SPLENECTOMIZED RATS FREE FROM BARTONELLA MURIS INFECTION
title_full_unstemmed THE METABOLISM OF COPPER AND IRON IN SPLENECTOMIZED RATS FREE FROM BARTONELLA MURIS INFECTION
title_short THE METABOLISM OF COPPER AND IRON IN SPLENECTOMIZED RATS FREE FROM BARTONELLA MURIS INFECTION
title_sort metabolism of copper and iron in splenectomized rats free from bartonella muris infection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132417/
https://www.ncbi.nlm.nih.gov/pubmed/19870310
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