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THE SURVIVAL OF VARIETIES OF TYPHUS VIRUS IN MOUSE PASSAGE, WITH PARTICULAR REFERENCE TO THE VIRUS OF BRILL'S DISEASE
The experiments above described have confirmed the observations of Laigret and Jadin that the European human typhus virus cannot be maintained for more than two generations in mice by brain-peritoneum passage; whereas the murine Mexican variety can be carried on by this method in mice through at lea...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1934
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132424/ https://www.ncbi.nlm.nih.gov/pubmed/19870303 |
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author | Savoor, Sadashivarao R. Velasco, Roberto |
author_facet | Savoor, Sadashivarao R. Velasco, Roberto |
author_sort | Savoor, Sadashivarao R. |
collection | PubMed |
description | The experiments above described have confirmed the observations of Laigret and Jadin that the European human typhus virus cannot be maintained for more than two generations in mice by brain-peritoneum passage; whereas the murine Mexican variety can be carried on by this method in mice through at least eleven passage generations. The fact that within eleven passages there is no attenuation of the murine virus renders it likely that this agent can continue in mice, in an inapparent form, without material modification. Brill's disease virus from three different isolations has behaved like the European type, a fact which strengthens the opinion previously expressed from this laboratory that Brill's disease represents an imported European strain of the classical European infection. |
format | Text |
id | pubmed-2132424 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1934 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21324242008-04-18 THE SURVIVAL OF VARIETIES OF TYPHUS VIRUS IN MOUSE PASSAGE, WITH PARTICULAR REFERENCE TO THE VIRUS OF BRILL'S DISEASE Savoor, Sadashivarao R. Velasco, Roberto J Exp Med Article The experiments above described have confirmed the observations of Laigret and Jadin that the European human typhus virus cannot be maintained for more than two generations in mice by brain-peritoneum passage; whereas the murine Mexican variety can be carried on by this method in mice through at least eleven passage generations. The fact that within eleven passages there is no attenuation of the murine virus renders it likely that this agent can continue in mice, in an inapparent form, without material modification. Brill's disease virus from three different isolations has behaved like the European type, a fact which strengthens the opinion previously expressed from this laboratory that Brill's disease represents an imported European strain of the classical European infection. The Rockefeller University Press 1934-08-31 /pmc/articles/PMC2132424/ /pubmed/19870303 Text en Copyright © Copyright, 1934, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Savoor, Sadashivarao R. Velasco, Roberto THE SURVIVAL OF VARIETIES OF TYPHUS VIRUS IN MOUSE PASSAGE, WITH PARTICULAR REFERENCE TO THE VIRUS OF BRILL'S DISEASE |
title | THE SURVIVAL OF VARIETIES OF TYPHUS VIRUS IN MOUSE PASSAGE, WITH PARTICULAR REFERENCE TO THE VIRUS OF BRILL'S DISEASE |
title_full | THE SURVIVAL OF VARIETIES OF TYPHUS VIRUS IN MOUSE PASSAGE, WITH PARTICULAR REFERENCE TO THE VIRUS OF BRILL'S DISEASE |
title_fullStr | THE SURVIVAL OF VARIETIES OF TYPHUS VIRUS IN MOUSE PASSAGE, WITH PARTICULAR REFERENCE TO THE VIRUS OF BRILL'S DISEASE |
title_full_unstemmed | THE SURVIVAL OF VARIETIES OF TYPHUS VIRUS IN MOUSE PASSAGE, WITH PARTICULAR REFERENCE TO THE VIRUS OF BRILL'S DISEASE |
title_short | THE SURVIVAL OF VARIETIES OF TYPHUS VIRUS IN MOUSE PASSAGE, WITH PARTICULAR REFERENCE TO THE VIRUS OF BRILL'S DISEASE |
title_sort | survival of varieties of typhus virus in mouse passage, with particular reference to the virus of brill's disease |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132424/ https://www.ncbi.nlm.nih.gov/pubmed/19870303 |
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