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A THERMOPRECIPITATION REACTION IN TRYPANOSOMA EQUIPERDUM INFECTION IN LABORATORY ANIMALS

There is a thermoprecipitinogenic substance in extracts of the spleen of rats, guinea pigs and rabbits infected with T. equiperdum. It does not appear to be within the body of the trypanosome itself. Antibodies to this heat-resistant precipitable substance were found in the serum of infected animals...

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Autor principal: Poindexter, Hildrus A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1934
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132435/
https://www.ncbi.nlm.nih.gov/pubmed/19870323
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author Poindexter, Hildrus A.
author_facet Poindexter, Hildrus A.
author_sort Poindexter, Hildrus A.
collection PubMed
description There is a thermoprecipitinogenic substance in extracts of the spleen of rats, guinea pigs and rabbits infected with T. equiperdum. It does not appear to be within the body of the trypanosome itself. Antibodies to this heat-resistant precipitable substance were found in the serum of infected animals. The antibody strength seems to be relatively less in the serum of rats than in the other animals but the power of extracts from the spleen of infected rats appeared to be equivalent to the power of similar extracts of the other animals. The antibody titer of the serum of rabbits was greater than in the case of the other two species investigated. This was shown not only by the reaction with the extracts of spleens of the same species, but also by the reaction with extracts of the spleens of similarly infected animals of other species.
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spelling pubmed-21324352008-04-18 A THERMOPRECIPITATION REACTION IN TRYPANOSOMA EQUIPERDUM INFECTION IN LABORATORY ANIMALS Poindexter, Hildrus A. J Exp Med Article There is a thermoprecipitinogenic substance in extracts of the spleen of rats, guinea pigs and rabbits infected with T. equiperdum. It does not appear to be within the body of the trypanosome itself. Antibodies to this heat-resistant precipitable substance were found in the serum of infected animals. The antibody strength seems to be relatively less in the serum of rats than in the other animals but the power of extracts from the spleen of infected rats appeared to be equivalent to the power of similar extracts of the other animals. The antibody titer of the serum of rabbits was greater than in the case of the other two species investigated. This was shown not only by the reaction with the extracts of spleens of the same species, but also by the reaction with extracts of the spleens of similarly infected animals of other species. The Rockefeller University Press 1934-10-31 /pmc/articles/PMC2132435/ /pubmed/19870323 Text en Copyright © Copyright, 1934, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Poindexter, Hildrus A.
A THERMOPRECIPITATION REACTION IN TRYPANOSOMA EQUIPERDUM INFECTION IN LABORATORY ANIMALS
title A THERMOPRECIPITATION REACTION IN TRYPANOSOMA EQUIPERDUM INFECTION IN LABORATORY ANIMALS
title_full A THERMOPRECIPITATION REACTION IN TRYPANOSOMA EQUIPERDUM INFECTION IN LABORATORY ANIMALS
title_fullStr A THERMOPRECIPITATION REACTION IN TRYPANOSOMA EQUIPERDUM INFECTION IN LABORATORY ANIMALS
title_full_unstemmed A THERMOPRECIPITATION REACTION IN TRYPANOSOMA EQUIPERDUM INFECTION IN LABORATORY ANIMALS
title_short A THERMOPRECIPITATION REACTION IN TRYPANOSOMA EQUIPERDUM INFECTION IN LABORATORY ANIMALS
title_sort thermoprecipitation reaction in trypanosoma equiperdum infection in laboratory animals
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132435/
https://www.ncbi.nlm.nih.gov/pubmed/19870323
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