Growth-inhibitory Activity and Downregulation of the Class II Tumor-suppressor Gene H-rev107 in Tumor Cell Lines and Experimental Tumors

The H-rev107 gene is a new class II tumor suppressor, as defined by its reversible downregulation and growth-inhibiting capacity in HRAS transformed cell lines. Overexpression of the H-rev107 cDNA in HRAS-transformed ANR4 hepatoma cells or in FE-8 fibroblasts resulted in 75% reduction of colony form...

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Detalles Bibliográficos
Autores principales: Sers, Christine, Emmenegger, Urban, Husmann, Knut, Bucher, Katharina, Andres, Ann-Catherine, Schäfer, Reinhold
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132501/
https://www.ncbi.nlm.nih.gov/pubmed/9049257

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