Affinity Modulation of Platelet Integrin α(IIb)β(3) by β(3)-Endonexin, a Selective Binding Partner of the β(3) Integrin Cytoplasmic Tail

Platelet agonists increase the affinity state of integrin α(IIb)β(3), a prerequisite for fibrinogen binding and platelet aggregation. This process may be triggered by a regulatory molecule(s) that binds to the integrin cytoplasmic tails, causing a structural change in the receptor. β(3)-Endonexin is...

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Detalles Bibliográficos
Autores principales: Kashiwagi, Hirokazu, Schwartz, Martin A., Eigenthaler, Martin, Davis, K.A., Ginsberg, Mark H., Shattil, Sanford J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132534/
https://www.ncbi.nlm.nih.gov/pubmed/9182673

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