Cargando…
Differential Stimulation of the Na(+)/H(+) Exchanger Determines Chloroquine Uptake in Plasmodium falciparum
Here we describe the identification and characterization of a physiological marker that is associated with the chloroquine-resistant (CQR) phenotype in the human malarial parasite Plasmodium falciparum. Single cell in vivo pH measurements revealed that CQR parasites consistently have an elevated cyt...
Autores principales: | Wünsch, Stefan, Sanchez, Cecilia P., Gekle, Michael, Große-Wortmann, Lars, Wiesner, Jochen, Lanzer, Michael |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132566/ https://www.ncbi.nlm.nih.gov/pubmed/9442109 |
Ejemplares similares
-
pH-dependence of the Plasmodium falciparum chloroquine resistance transporter is linked to the transport cycle
por: Berger, Fiona, et al.
Publicado: (2023) -
The Knock-Down of the Chloroquine Resistance Transporter PfCRT Is Linked to Oligopeptide Handling in Plasmodium falciparum
por: Sanchez, Cecilia P., et al.
Publicado: (2022) -
Multiple Drugs Compete for Transport via the Plasmodium falciparum Chloroquine Resistance Transporter at Distinct but Interdependent Sites
por: Bellanca, Sebastiano, et al.
Publicado: (2014) -
On the Mechanism of Chloroquine Resistance in Plasmodium falciparum
por: Chinappi, Mauro, et al.
Publicado: (2010) -
Chloroquine-resistant Plasmodium falciparum in Pakistan
por: Khattak, Aamer Ali, et al.
Publicado: (2021)