A Dominant Mutant of Inner Centromere Protein (INCENP), a Chromosomal Protein, Disrupts Prometaphase Congression and Cytokinesis

INCENP is a tightly bound chromosomal protein that transfers to the spindle midzone at the metaphase/anaphase transition. Here, we show that an INCENP truncation mutant (INCENP(382–839)) associates with microtubules but does not bind to chromosomes, and coats the entire spindle throughout mitosis. F...

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Detalles Bibliográficos
Autores principales: Mackay, Alastair M., Ainsztein, Alexandra M., Eckley, D. Mark, Earnshaw, William C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132686/
https://www.ncbi.nlm.nih.gov/pubmed/9490714

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