Cargando…
OCI-5/GPC3, a Glypican Encoded by a Gene That Is Mutated in the Simpson-Golabi-Behmel Overgrowth Syndrome, Induces Apoptosis in a Cell Line–specific Manner
OCI-5/GPC3 is a member of the glypican family. Glypicans are heparan sulfate proteoglycans that are bound to the cell surface through a glycosyl-phosphatidylinositol anchor. It has recently been shown that the OCI-5/GPC3 gene is mutated in patients with the Simpson-Golabi-Behmel Syndrome (SGBS), an...
Autores principales: | Gonzalez, Alfonso Dueñas, Kaya, Mitsunori, Shi, Wen, Song, Howard, Testa, Joseph R., Penn, Linda Z., Filmus, Jorge |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132788/ https://www.ncbi.nlm.nih.gov/pubmed/9628896 |
Ejemplares similares
-
Glypican-3–Deficient Mice Exhibit Developmental Overgrowth and Some of the Abnormalities Typical of Simpson-Golabi-Behmel Syndrome
por: Cano-Gauci, Danielle F., et al.
Publicado: (1999) -
Loss-of-function mutations and global rearrangements in GPC3 in patients with Simpson–Golabi–Behmel syndrome
por: Shimojima, Keiko, et al.
Publicado: (2016) -
Simpson-Golabi-Behmel syndrome types I and II
por: Tenorio, Jair, et al.
Publicado: (2014) -
Novel GPC3 Gene Mutation in Simpson-Golabi-Behmel Syndrome with Endocrine Anomalies: A Case Report
por: Bu, W, et al.
Publicado: (2022) -
Simpson-Golabi-Behmel-Syndrome in Dichorionic-Diamniotic Twin Pregnancy
por: Reischer, Theresa, et al.
Publicado: (2021)