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Regulated Targeting of BAX to Mitochondria
The proapoptotic protein BAX contains a single predicted transmembrane domain at its COOH terminus. In unstimulated cells, BAX is located in the cytosol and in peripheral association with intracellular membranes including mitochondria, but inserts into mitochondrial membranes after a death signal. T...
Autores principales: | Goping, Ing Swie, Gross, Atan, Lavoie, Josée N., Nguyen, Mai, Jemmerson, Ronald, Roth, Kevin, Korsmeyer, Stanley J., Shore, Gordon C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132805/ https://www.ncbi.nlm.nih.gov/pubmed/9763432 |
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