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Spindle Checkpoint Protein Xmad1 Recruits Xmad2 to Unattached Kinetochores

The spindle checkpoint prevents the metaphase to anaphase transition in cells containing defects in the mitotic spindle or in chromosome attachment to the spindle. When the checkpoint protein Xmad2 is depleted from Xenopus egg extracts, adding Xmad2 to its endogenous concentration fails to restore t...

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Detalles Bibliográficos
Autores principales: Chen, Rey-Huei, Shevchenko, Andrej, Mann, Matthias, Murray, Andrew W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132829/
https://www.ncbi.nlm.nih.gov/pubmed/9786942