Induction of Integral Membrane PAM Expression in AtT-20 Cells Alters the Storage and Trafficking of POMC and PC1

Peptidylglycine α-amidating monooxygenase (PAM) is an essential enzyme that catalyzes the COOH-terminal amidation of many neuroendocrine peptides. The bifunctional PAM protein contains an NH(2)-terminal monooxygenase (PHM) domain followed by a lyase (PAL) domain and a transmembrane domain. The cytos...

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Detalles Bibliográficos
Autores principales: Ciccotosto, Giuseppe D., Schiller, Martin R., Eipper, Betty A., Mains, Richard E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Regular Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132922/
https://www.ncbi.nlm.nih.gov/pubmed/9971741

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