The NH(2) Terminus of Titin Spans the Z-Disc: Its Interaction with a Novel 19-kD Ligand (T-cap) Is Required for Sarcomeric Integrity

Titin is a giant elastic protein in vertebrate striated muscles with an unprecedented molecular mass of 3–4 megadaltons. Single molecules of titin extend from the Z-line to the M-line. Here, we define the molecular layout of titin within the Z-line; the most NH(2)-terminal 30 kD of titin is located...

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Detalles Bibliográficos
Autores principales: Gregorio, Carol C., Trombitás, Karoly, Centner, Thomas, Kolmerer, Bernhard, Stier, Gunter, Kunke, Kathleen, Suzuki, Koichi, Obermayr, Franz, Herrmann, Bernhard, Granzier, Henk, Sorimachi, Hiroyuki, Labeit, Siegfried
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Regular Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132961/
https://www.ncbi.nlm.nih.gov/pubmed/9817758

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