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Two Functional States of the CD11b A-Domain: Correlations with Key Features of Two Mn(2+)-complexed Crystal Structures
In the presence of bound Mn(2+), the three- dimensional structure of the ligand-binding A-domain from the integrin CR3 (CD11b/CD18) is shown to exist in the “open” conformation previously described only for a crystalline Mg(2+) complex. The open conformation is distinguished from the “closed” form b...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1998
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132978/ https://www.ncbi.nlm.nih.gov/pubmed/9852148 |