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Recruitment and the Role of Nuclear Localization in Polyglutamine-mediated Aggregation
The inherited neurodegenerative diseases caused by an expanded glutamine repeat share the pathologic feature of intranuclear aggregates or inclusions (NI). Here in cell-based studies of the spinocerebellar ataxia type-3 disease protein, ataxin-3, we address two issues central to aggregation: the rol...
Autores principales: | Perez, Matthew K., Paulson, Henry L., Pendse, Sagun J., Saionz, Sarah J., Bonini, Nancy M., Pittman, Randall N. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132986/ https://www.ncbi.nlm.nih.gov/pubmed/9852144 |
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