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Complementary Roles for Receptor Clustering and Conformational Change in the Adhesive and Signaling Functions of Integrin α(IIb)β(3)
Integrin α(IIb)β(3) mediates platelet aggregation and “outside-in” signaling. It is regulated by changes in receptor conformation and affinity and/or by lateral diffusion and receptor clustering. To document the relative contributions of conformation and clustering to α(IIb)β(3) function, α(IIb) was...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1998
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133003/ https://www.ncbi.nlm.nih.gov/pubmed/9647659 |