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Structural and Functional Regulation of Tight Junctions by RhoA and Rac1 Small GTPases
Tight junctions (TJ) govern ion and solute diffusion through the paracellular space (gate function), and restrict mixing of membrane proteins and lipids between membrane domains (fence function) of polarized epithelial cells. We examined roles of the RhoA and Rac1 GTPases in regulating TJ structure...
Autores principales: | Jou, Tzuu-Shuh, Schneeberger, Eveline E., James Nelson, W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133025/ https://www.ncbi.nlm.nih.gov/pubmed/9660866 |
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