Dual Actions of Sphingosine-1-Phosphate: Extracellular through the G(i)-coupled Receptor Edg-1 and Intracellular to Regulate Proliferation and Survival

Sphingosine-1-phosphate (SPP), a bioactive lipid, acts both intracellularly and extracellularly to cause pleiotropic biological responses. Recently, we identified SPP as a ligand for the G protein–coupled receptor Edg-1 (Lee, M.-J., J.R. Van Brocklyn, S. Thangada, C.H. Liu, A.R. Hand, R. Menzeleev,...

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Detalles Bibliográficos
Autores principales: Van Brocklyn, James R., Lee, Menq-Jer, Menzeleev, Ramil, Olivera, Ana, Edsall, Lisa, Cuvillier, Olivier, Thomas, Dianne M., Coopman, Peter J.P., Thangada, Shobha, Liu, Catherine H., Hla, Timothy, Spiegel, Sarah
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133030/
https://www.ncbi.nlm.nih.gov/pubmed/9660876

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